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The Effect of Genetic Polymorphisms of Cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on Drug-Resistant Epilepsy in Turkish Children

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dc.contributor.authorSeven, Mehmet
dc.contributor.authorBatar, Bahadir
dc.contributor.authorUnal, Selin
dc.contributor.authorYesil, GÖZDE
dc.contributor.authorYuksel, Adnan
dc.contributor.authorGuven, Mehmet
dc.contributor.institutionauthorYEŞİL, GÖZDE
dc.date.accessioned2020-10-30T00:35:37Z
dc.date.available2020-10-30T00:35:37Z
dc.date.issued2014-04-01T00:00:00Z
dc.description.abstractDespite the availability of several antiepileptic drugs, drug resistance remains one of the major challenges in epilepsy therapy. Genetic factors are known to play a significant role in the prognosis and treatment of epilepsy. The aim of this study was to determine the frequencies of alleles for CYP2C9, CYP2C19, and CYP2D6 genes in Turkish children with epilepsy, and to investigate the relationship between the genetic polymorphism of these genes with multiple drug resistance in epilepsy patients.
dc.identifier.citationSeven M., Batar B., Unal S., Yesil G., Yuksel A., Guven M., -The Effect of Genetic Polymorphisms of Cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on Drug-Resistant Epilepsy in Turkish Children-, MOLECULAR DIAGNOSIS & THERAPY, cilt.18, ss.229-236, 2014
dc.identifier.doi10.1007/s40291-013-0078-8
dc.identifier.scopus84897399856
dc.identifier.urihttp://hdl.handle.net/20.500.12645/27274
dc.identifier.wosWOS:000333208200010
dc.titleThe Effect of Genetic Polymorphisms of Cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on Drug-Resistant Epilepsy in Turkish Children
dc.typeArticle
dspace.entity.typePublication
local.avesis.idfdbe988a-39eb-4653-9abc-727c88992b1a
local.indexed.atWOS
local.indexed.atScopus
local.publication.isinternational1
relation.isAuthorOfPublicationb653abbc-327a-4b3b-a227-f3344d8d6b70
relation.isAuthorOfPublication.latestForDiscoveryb653abbc-327a-4b3b-a227-f3344d8d6b70

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