Publication:
Dose and time dependent ototoxicity of aspartame in rats

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2017-01-01

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TUGRUL, Selahattin
Ozturan, ORHAN
Dogan, REMZİ
Gedik, Ozge
SJOSTRAND, Alev Pektas
Yildirim, YAVUZ SELİM

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Abstract

Conclusion: Low-dose administration of Aspartame (Ap) did not produce a significant ototoxic effect at the end of the 6th month. However, duration of the ototoxic effect is shortened and severity of the effect is increased as dose and duration of Ap administration is increased.

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Ozturan O., Dogan R., TUGRUL S., Gedik O., SJOSTRAND A. P. , Yildirim Y. S. , -Dose and time dependent ototoxicity of aspartame in rats-, ACTA OTO-LARYNGOLOGICA, cilt.137, ss.421-425, 2017
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