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Somatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis

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dc.contributor.authorErson-Omay, E. Zeynep
dc.contributor.authorCaglayan, Ahmet Okay
dc.contributor.authorSchultz, Nikolaus
dc.contributor.authorWeinhold, Nils
dc.contributor.authorOmay, S. Bulent
dc.contributor.authorÖZDUMAN, Koray
dc.contributor.authorKoksal, Yavuz
dc.contributor.authorLi, Jie
dc.contributor.authorHarmanci, Akdes Serin
dc.contributor.authorClark, Victoria
dc.contributor.authorCarrion-Grant, Geneive
dc.contributor.authorBaranoski, Jacob
dc.contributor.authorCaglar, CANER
dc.contributor.authorBarak, Tanyeri
dc.contributor.authorCoskun, Suleyman
dc.contributor.authorBaran, Burcin
dc.contributor.authorKose, Dogan
dc.contributor.authorSun, Jia
dc.contributor.authorBakircioglu, Mehmet
dc.contributor.authorGunel, Jennifer Moliterno
dc.contributor.authorPamir, M. Necmettin
dc.contributor.authorMishra-Gorur, Ketu
dc.contributor.authorBilguvar, Kaya
dc.contributor.authorYasuno, Katsuhito
dc.contributor.authorVortmeyer, Alexander
dc.contributor.authorHuttner, Anita J.
dc.contributor.authorSander, Chris
dc.contributor.authorGunel, Murat
dc.contributor.institutionauthorÇAĞLAR, CANER
dc.date.accessioned2021-08-03T20:59:15Z
dc.date.available2021-08-03T20:59:15Z
dc.date.issued2015-10-01T00:00:00Z
dc.description.abstractBackground. Malignant high-grade gliomas (HGGs), including the most aggressive form, glioblastoma multiforme, show significant clinical and genomic heterogeneity. Despite recent advances, the overall survival of HGGs and their response to treatment remain poor. In order to gain further insight into disease pathophysiology by correlating genomic landscape with clinical behavior, thereby identifying distinct HGG molecular subgroups associated with improved prognosis, we performed a comprehensive genomic analysis.
dc.identifier.citationErson-Omay E. Z. , Caglayan A. O. , Schultz N., Weinhold N., Omay S. B. , ÖZDUMAN K., Koksal Y., Li J., Harmanci A. S. , Clark V., et al., -Somatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis-, NEURO-ONCOLOGY, cilt.17, sa.10, ss.1356-1364, 2015
dc.identifier.doi10.1093/neuonc/nov027
dc.identifier.scopus84943372151
dc.identifier.urihttp://hdl.handle.net/20.500.12645/29109
dc.identifier.wosWOS:000364783100007
dc.titleSomatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id52a7b7d2-6625-4e5c-94be-fd818db55416
local.indexed.atWOS
local.indexed.atScopus
local.publication.isinternational1
relation.isAuthorOfPublication6e33515f-c9c7-4020-bcae-a2048eccbe74
relation.isAuthorOfPublication.latestForDiscovery6e33515f-c9c7-4020-bcae-a2048eccbe74

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