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Synthesis, Complexation, and Biological Activity Studies of 4-Aminomethyl-7,8-dihydroxy Coumarines and Their Crown Ether Derivatives

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dc.contributor.authorGumus, Arzu
dc.contributor.authorKaradeniz, Seref
dc.contributor.authorUgras, Halil Ibrahim
dc.contributor.authorBulut, Mustafa
dc.contributor.authorCakir, Umit
dc.contributor.authorGoren, AHMET CEYHAN
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2020-10-29T13:04:19Z
dc.date.available2020-10-29T13:04:19Z
dc.date.issued2010-09-01T00:00:00Z
dc.description.abstractThe article focuses synthesis of novel 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives. The purified novel coumarins and their crown ether derivatives were identified by (1)H NMR, (13)C NMR, mass spectrometry and elemental analysis. The 1:1 binding constants of Ca(2+), Mg(2+), Fe(2+), Zn(2+), Ni(2+), Cd(2+), Co(2+), and Mn(2+) ions at 25 degrees C +/- 0.1 with the 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives estimated using extraction procedure with Inductively Coupled Plasma-Atomic Emission Spectroscopy in dichloromethane/water membrane systems. Synthesized compounds were investigated for complexation and biological activity properties. Best results in biological activity studies were observed for antioxidant activity.
dc.identifier.citationGumus A., Karadeniz S., Ugras H. I. , Bulut M., Cakir U., Goren A. C. , -Synthesis, Complexation, and Biological Activity Studies of 4-Aminomethyl-7,8-dihydroxy Coumarines and Their Crown Ether Derivatives-, JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.47, ss.1127-1133, 2010
dc.identifier.doi10.1002/jhet.435
dc.identifier.scopus77956912464
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25055
dc.identifier.wosWOS:000282489200020
dc.titleSynthesis, Complexation, and Biological Activity Studies of 4-Aminomethyl-7,8-dihydroxy Coumarines and Their Crown Ether Derivatives
dc.typeArticle
dspace.entity.typePublication
local.avesis.id036288d3-7372-41d5-9d53-d9d2f5611c30
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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