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The role of diffusion-weighted MRI and contrast-enhanced MRI for differentiation between solid renal masses and renal cell carcinoma subtypes

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dc.contributor.authorSerter, Asli
dc.contributor.authorONUR, MEHMET RUHİ
dc.contributor.authorÇOBAN, Ganime
dc.contributor.authorYILDIZ, PELİN
dc.contributor.authorArmagan, Abdullah
dc.contributor.authorKocakoc, Ercan
dc.contributor.institutionauthorÇOBAN, GANİME
dc.contributor.institutionauthorYILDIZ, PELİN
dc.date.accessioned2020-10-22T20:21:43Z
dc.date.available2020-10-22T20:21:43Z
dc.date.issued2020-09-01T00:00:00Z
dc.description.abstractPurpose To assess the value of diffusion-weighted magnetic resonance imaging (DW-MRI) and contrast-enhanced MRI (CE-MRI) for differentiation between benign and malignant solid renal masses, renal cell carcinoma (RCC) subtypes, oncocytomas, and lipid-poor angiomyolipomas (LP-AML). Methods Minimum or lowest -apparent diffusion coefficient- (ADC(1)) and representative ADC values (ADC(2)) of 112 renal masses (n: 46 benign renal mass,n: 66 malignant renal mass) were measured on DW-MRI images (b50, 400, 800 s/mm(2)). Signal intensity (SI) measurements were performed in normal renal parenchyma and most avid enhanced area of the renal masses at precontrast, corticomedullary, and nephrographic phases on CE-MRI. Contrast enhancement rate (CER) and contrast enhancement index (CEI) values of renal masses were compared between benign-malignant renal masses and RCC subtypes, oncocytomas, and LP-AMLs. Results There was no significant difference between ADC(1), ADC(2)values, and SI of benign and malignant renal masses (p = 0.721,p = 0.255,p = 0.872). Mean ADC(1)and ADC(2)values of clear cell RCCs were significantly higher than nonclear cell RCCs (p = 0.005p = 0.002). Mean CER value of clear cell RCCs was significantly higher than nonclear cell RCCs in nephrographic phase (p = 0.003). Mean CEI values of clear cell RCCs were significantly higher than nonclear cell RCCs in the corticomedullary and nephrographic phase (p = 0.027 vs. 0.008). LP-AMLs were differentiated from other renal masses with wash-out phenomenon. Conclusion Combined usage of ADC, SI, CER, and CEI values may be useful for discrimination between RCC subtypes, oncocytomas, and lipid-poor AMLs.
dc.identifier.citationSerter A., ONUR M. R. , ÇOBAN G., YILDIZ P., Armagan A., Kocakoc E., -The role of diffusion-weighted MRI and contrast-enhanced MRI for differentiation between solid renal masses and renal cell carcinoma subtypes-, ABDOMINAL RADIOLOGY, 2020
dc.identifier.doi10.1007/s00261-020-02742-w
dc.identifier.pubmed32930832
dc.identifier.scopus85091099422
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24708
dc.identifier.wosWOS:000569576600001
dc.titleThe role of diffusion-weighted MRI and contrast-enhanced MRI for differentiation between solid renal masses and renal cell carcinoma subtypes
dc.typeArticle
dspace.entity.typePublication
local.avesis.idde3bb9d9-2ffa-46fd-bb9d-9d6ba910c0ee
local.publication.isinternational1
relation.isAuthorOfPublication92813154-621b-468c-8399-8510ae43f718
relation.isAuthorOfPublication4c9a734d-36ee-4704-9e15-7012fd2ca3fb
relation.isAuthorOfPublication.latestForDiscovery92813154-621b-468c-8399-8510ae43f718
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