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Impact of Helicobacter pylori infection on severity of psoriasis and response to treatment

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dc.contributor.authorOnsun, NAHİDE
dc.contributor.authorSu, Ozlem
dc.contributor.authorBEYCAN, Ismet
dc.contributor.authorOZKAYA, Dilek Biyik
dc.contributor.authorSenocak, Mustafa
dc.contributor.institutionauthorONSUN, NAHIDE
dc.contributor.institutionauthorSU KÜÇÜK, ÖZLEM
dc.date.accessioned2019-10-05T12:53:44Z
dc.date.available2019-10-05T12:53:44Z
dc.date.issued2012-01-01
dc.description.abstractThe aims of this study were to determine the prevalence of H. pylori seropositivity in patients with psoriasis, to evaluate the relationship between PASI (Psoriasis Area and Severity Index) scores and H. pylori infection, and to assess the impact of H. pylori infection on the response to treatment. A total of 300 patients with psoriasis and 150 non-psoriatic healthy controls were enrolled in the study. Patient PAST scores were recorded and H. pylori stool antigen tests performed in both patients and controls. Fifty patients with H. pylori infections were randomly assigned to one of two groups, one of which received acitretin with H. pylori treatment and the other acitretin alone. Statistical analyses were performed using chi-square and logistic regression tests. PASI scores were significantly higher in patients with H. pylori infections. Treatment aimed at eradicating H. pylori infection enhanced the effectiveness of acitretin therapy and shortened response times. Our results suggest that H. pylori infection plays a role in the severity of psoriasis, and that eradicating such infections enhances the effectiveness of psoriasis treatment.
dc.identifier
dc.identifier.citationOnsun N., ULUSAL H. A. , Su O., BEYCAN I., OZKAYA D. B. , Senocak M., -Impact of Helicobacter pylori infection on severity of psoriasis and response to treatment-, EUROPEAN JOURNAL OF DERMATOLOGY, cilt.22, ss.117-120, 2012
dc.identifier.doi10.1684/ejd.2011.1579
dc.identifier.pubmed22063790
dc.identifier.scopus84857804163
dc.identifier.urihttps://hdl.handle.net/20.500.12645/849
dc.identifier.wosWOS:000301818400022
dc.titleImpact of Helicobacter pylori infection on severity of psoriasis and response to treatment
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameCumhuriyet Hemşirelik Dergisi
local.avesis.id1320dea5-9c81-49f9-8d03-7689976911f2
local.avesis.response719
local.org.facultyTıp Fakültesi
local.publication.isinternational1
relation.isAuthorOfPublication1ebc9a95-ecf2-4c81-9f74-3c5fb32a9406
relation.isAuthorOfPublicationfd8dc121-9bbe-4ee4-a2fd-5e237676169d
relation.isAuthorOfPublication.latestForDiscoveryfd8dc121-9bbe-4ee4-a2fd-5e237676169d
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