Publication:
Distribution of Hepatitis C Virus genotypes in patients with chronic Hepatitis C infection in Eastern Turkey

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dc.contributor.authorOzer, Turkan Toka
dc.contributor.authorBerktas, Mustafa
dc.contributor.authorYAMAN, GÖRKEM
dc.contributor.authorErkoc, Reha
dc.date.accessioned2020-10-22T18:36:58Z
dc.date.available2020-10-22T18:36:58Z
dc.date.issued2015-01-01T00:00:00Z
dc.description.abstractViral hepatitis is one of the most important liver diseases in the world. Duration of hepatitis C virus (HCV) infection and response to standard therapy is strongly related to HCV genotypes. Geographical distribution of HCV genotypes is also important for epidemiological studies. We aimed to determine the distribution of HCV genotypes and their prevalence in Eastern Turkey. Fifty eight Anti-HCV, LIA, HCV-RNA positive patients (35 male, 23 female) were included in this study. Genotypes were determined by reverse dot-blot hybridization method. Distribution of HCV genotypes in 58 patients were as follows: Genotype 1b in 53.4% (n=31), genotype 1a in 36.2% (n=21), genotype 1, 3, 4, 1a/1b in 1.7 % (n=1) for each. Genotype 1 was identified as the dominant type in 93.2% (n=54). HCV genotype could not be identified in 3.4% (n=2) patients. Genotype 1b was the most common HCV genotype in our region and this result is in accordance with the previous data of Turkey. Although genotype 1b is predominant, detection of genotype 1a in studies show that genotyping is beneficial for cost-effectiveness of chronic HCV infection. Thus, genotyping of HCV patients in our region guide clinicians in terms of monitoring and treatment success.
dc.identifier.citationOzer T. T. , Berktas M., YAMAN G., Erkoc R., -Distribution of Hepatitis C Virus genotypes in patients with chronic Hepatitis C infection in Eastern Turkey-, BIOMEDICAL RESEARCH-INDIA, cilt.26, ss.697-701, 2015
dc.identifier.scopus84940977614
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24262
dc.identifier.wosWOS:000364543800017
dc.titleDistribution of Hepatitis C Virus genotypes in patients with chronic Hepatitis C infection in Eastern Turkey
dc.typeArticle
dspace.entity.typePublication
local.avesis.id99f2866b-db7f-4be4-b06e-3587a071ee4f
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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