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The Prevalence and Outcomes of Thrombocytopenia in a Neonatal Intensive Care Unit: A Three-Year Report

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dc.contributor.authorBOLAT, FATİH
dc.contributor.authorKilic, Suar Caki
dc.contributor.authorOFLAZ, MEHMET BURHAN
dc.contributor.authorGULHAN, Elif
dc.contributor.authorKAYA, Ali
dc.contributor.authorGÜVEN, AHMET SAMİ
dc.contributor.authorAYGUNES, Utku
dc.contributor.authorIcagasioglu, Dilara
dc.contributor.authorGÜLTEKİN, ASIM
dc.contributor.institutionauthorİÇAĞASIOĞLU, DİLARA FÜSUN
dc.date.accessioned2020-10-29T14:15:32Z
dc.date.available2020-10-29T14:15:32Z
dc.date.issued2012-11-01T00:00:00Z
dc.description.abstractNeonatal thrombocytopenia is one of the most common hematologic disorders in neonatal intensive care units (NICUs). The purpose of this study was to determine the prevalence of thrombocytopenia and whether thrombocytopenia has an effect on the occurrence of intraventricular hemorrhage (IVH) >= grade 2 and on mortality rate. This study was carried out retrospectively in neonates admitted to NICU of Cumhuriyet University in Sivas, Turkey, between 2009 and 2012. Among 2218 neonates evaluated, 208 (9.4%) developed thrombocytopenia. The prevalence of IVH >= grade 2 was more in infants with thrombocytopenia (7.2%) than in those without thrombocytopenia (4.4%), although this was not statistically significant (P=.08). In univariate analysis, IVH >= grade 2 was higher in cases with very severe thrombocytopenia (35.7%, n = 5) than in those with mild (2.1%, n = 2), moderate (4.7%, n = 3), and severe thrombocytopenia (15.2%, n = 5) (P=.04). Multivariate logistic regression analysis showed that birth weight = 2 (OR 7.3, 95% CI 4.1-12.1; P=.001) were significant risk factors for mortality. The results of our study suggest that outcomes of neonates with thrombocytopenia depend not only on platelet count but also on decreased gestational age or birth weight, prenatal factors, and sepsis.
dc.identifier.citationBOLAT F., Kilic S. C. , OFLAZ M. B. , GULHAN E., KAYA A., GÜVEN A. S. , AYGUNES U., Icagasioglu D., GÜLTEKİN A., -The Prevalence and Outcomes of Thrombocytopenia in a Neonatal Intensive Care Unit: A Three-Year Report-, PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.29, ss.710-720, 2012
dc.identifier.doi10.3109/08880018.2012.725454
dc.identifier.scopus84867921124
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25299
dc.identifier.wosWOS:000310315000007
dc.titleThe Prevalence and Outcomes of Thrombocytopenia in a Neonatal Intensive Care Unit: A Three-Year Report
dc.typeArticle
dspace.entity.typePublication
local.avesis.id229c7d36-911b-40a5-aa89-2237acf92225
local.publication.isinternational1
relation.isAuthorOfPublicationd6e0d341-df58-438f-bfac-96639f63d5d3
relation.isAuthorOfPublication.latestForDiscoveryd6e0d341-df58-438f-bfac-96639f63d5d3
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