Publication:
Comparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury

dc.contributor.authorDİKER, Nurettin
dc.contributor.authorAytac, Duygu
dc.contributor.authorHelvacioglu, Fatma
dc.contributor.authorOguz, Yener
dc.contributor.institutionauthorDİKER, NURETTİN
dc.date.accessioned2020-06-05T20:59:46Z
dc.date.available2020-06-05T20:59:46Z
dc.date.issued2020-03-01T00:00:00Z
dc.description.abstractThe aim of the present study was to investigate the therapeutic effects of 660-nm and 880-nm photobiomodulation therapy (PBMT) following inferior alveolar nerve (IAN) crush injury. Following the nerve crush injuries of IAN, 36 Wistar rats were randomly divided into three groups as follows: (1) control, (2) 660-nm PBMT, and (3) 808-nm PBMT (GaAlAs laser, 100 J/cm(2), 70 mW, 0.028-cm(2) beam). PBMT was started immediately after surgery and performed once every 3 days during the postoperative period. At the end of the 30-day treatment period, histopathological and histomorphometric evaluations of tissue sections were made under a light and electron microscope. The ratio of the inner axonal diameter to the total outer axonal diameter (g-ratio) and the number of axons per square micrometer were evaluated. In the 808-nm PBMT group, the number of nerve fibers with suboptimal g-ratio ranges of 0-0.49 (p < 0.001) is significantly lower than expected, which indicates better rate of myelinization in the 808-nm PBMT group. The number of axons per square micrometer was significantly higher in the 808-nm PBMT group when compared with the control (p < 0.001) and 660-nm PBMT group (p = 0.010). The data and the histopathological investigations suggest that the PBMT with the 808-nm wavelength along with its settings was able to enhance IAN regeneration after nerve crush injury.
dc.identifier.citationDİKER N., Aytac D., Helvacioglu F., Oguz Y., -Comparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury-, LASERS IN MEDICAL SCIENCE, cilt.35, ss.413-420, 2020
dc.identifier.doi10.1007/s10103-019-02838-w
dc.identifier.pubmed31273571
dc.identifier.scopus85068829803
dc.identifier.urihttps://hdl.handle.net/20.500.12645/18066
dc.identifier.wosWOS:000513211100014
dc.language.isoen
dc.titleComparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury
dc.typeArticle
dspace.entity.typePublication
local.avesis.id6556fb1c-687c-4636-a7e6-e74734ad0805
local.publication.isinternational1
relation.isAuthorOfPublicationaad04544-dd5e-45d4-a15d-24365e416f6e
relation.isAuthorOfPublication.latestForDiscoveryaad04544-dd5e-45d4-a15d-24365e416f6e
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