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Brain Perfusion MRI Findings in Patients with Behcet-s Disease

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dc.contributor.authorAlkan, ALPAY
dc.contributor.authorGOKTAN, Asli
dc.contributor.authorKarincaoglu, Yelda
dc.contributor.authorKAMIŞLI, SUAT
dc.contributor.authorDogan, Metin
dc.contributor.authorOztanir, Namik
dc.contributor.authorTuran, Nergiz
dc.contributor.authorKOCAKOC, Ercan
dc.contributor.institutionauthorALKAN, ALPAY
dc.contributor.institutionauthorÖZTANIR, MUSTAFA NAMIK
dc.date.accessioned2020-10-29T21:59:06Z
dc.date.available2020-10-29T21:59:06Z
dc.date.issued2012-01-01T00:00:00Z
dc.description.abstractObjective. To search brain perfusion MRI (pMRI) changes in Behcet-s disease (BD) with or without neurological involvement. Materials and Method. The pMRI were performed in 34 patients with BD and 16 healthy controls. Based on neurologic examination and post-contrast MRI, 12 patients were classified as Neuro-Behcet (group 1, NBD) and 22 patients as BD without neurological involvement (group 2). Mean transit time (MTT), time to peak (TTP), relative cerebral blood volume (rCBV), and relative cerebral blood flow (rCBF) were obtained and compared to those of healthy control group (group 3). Results. There was a significant difference in the MTT and rCBF within the pons and parietal cortex in groups 1 and 2. rCBV increased in cerebral pedicle in group 1 compared with groups 2 and 3. In the temporal lobe white matter, prolonged MTT and decreased rCBF were found in groups 1 and 2. In the corpus striatum, internal capsule, and periventricular white matter, rCBF increased in group 1 compared with group 3 and decreased in groups 1 and 2. Conclusion. Brain pMRI is a very sensitive method to detect brain involvement in patients with BD and aids the clinical diagnosis of NBD, especially in patients with negative MRI findings.
dc.identifier.citationAlkan A., GOKTAN A., Karincaoglu Y., KAMIŞLI S., Dogan M., Oztanir N., Turan N., KOCAKOC E., -Brain Perfusion MRI Findings in Patients with Behcet-s Disease-, SCIENTIFIC WORLD JOURNAL, 2012
dc.identifier.doi10.1100/2012/261502
dc.identifier.pubmed22654579
dc.identifier.scopus84861071886
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26493
dc.identifier.urihttps://www.hindawi.com/journals/tswj/2012/261502/
dc.identifier.wosWOS:000304774000001
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMRI
dc.titleBrain Perfusion MRI Findings in Patients with Behcet-s Disease
dc.typeArticle
dspace.entity.typePublication
local.avesis.ida5e14313-1232-451c-964b-b3e149d6e938
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
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