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LC-MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes

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dc.contributor.authorKose, Leyla Polat
dc.contributor.authorGÜLÇİN, İlhami
dc.contributor.authorGoren, AHMET CEYHAN
dc.contributor.authorNAMIESNIK, Jacek
dc.contributor.authorLeticia Martinez-Ayala, Alma
dc.contributor.authorGorinstein, Shela
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2020-10-29T21:16:33Z
dc.date.available2020-10-29T21:16:33Z
dc.date.issued2015-11-15T00:00:00Z
dc.description.abstractGalanga (Alpinia officinarum Hance) is a pungent and aromatic rhizome, which is a member of the ginger family (Zingiberaceae). The rhizomes of this plant have been used as a traditional medicine in far east countries for relieving stomach ache, invigorating the circulatory system, treating colds, and reducing swelling. The aim of this study was to investigate antioxidant and anticholinergic properties of galanga. For this purpose, we elucidated the antioxidant activity of water (WEG), ethanol (EEG) and water/ethanol (50:50 v/v WEEG) extracts of galanga by different in vitro antioxidant assays. Radical scavenging activities of galanga extracts were performed by 2,2-dipheny1-1-picrylhydrazyl (DPPH center dot) and 2,2--azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS(center dot+)) radical scavenging assays. Also, reducing power galanga extracts were evaluated by Cu2+-Cu+ reducing (CUPRAC) and Fe3+-Fe2+ reducing and [Fe3+-(TPTZ)(2)](3+) [Fe2+-(TPTZ)(2)](2+) (FRAP) abilities. Finally, Fe2+ chelating activity by pipyrdyl reagent and anticholinergic activities of galanga extracts were realised. All galanga extracts demonstrated antioxidant activity. alpha-Tocopherol ((2R)-2,5,7,8-tetramethyl-2-1(4R,8R)-(4,8,12-trimethyltridecyl)]-6-chromanol), trolox (3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl- 2H-1-benzopyran-2-carboxylic acid), butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) were used as positive controls. On the other hand, IC0 values were calculated for DPPH center dot, ABTS*(+) scavenging Fe2+ chelating, and anticholinergic effects of galanga extracts. This study clearly showed that galanga had marked antioxidant, anticholinergic effect, reducing ability, radical scavenging and metal binding activities. (C) 2015 Elsevier B.V. All rights reserved.
dc.identifier.citationKose L. P. , GÜLÇİN İ., Goren A. C. , NAMIESNIK J., Leticia Martinez-Ayala A., Gorinstein S., -LC-MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes-, INDUSTRIAL CROPS AND PRODUCTS, cilt.74, ss.712-721, 2015
dc.identifier.doi10.1016/j.indcrop.2015.05.034
dc.identifier.scopus84936108034
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26228
dc.identifier.wosWOS:000360948900091
dc.titleLC-MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes
dc.typeArticle
dspace.entity.typePublication
local.avesis.id810d4a38-7464-4a34-80fe-b0f3f60a32ca
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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