Publication: Evaluation of oxidative status in patients with chronic periodontitis and polycystic ovary syndrome: A cross-sectional study.
dc.contributor.author | Saglam, Ebru | |
dc.contributor.author | Canakci, Cenk Fatih | |
dc.contributor.author | Sebin, Saime Ozbek | |
dc.contributor.author | Saruhan, Nesrin | |
dc.contributor.author | Ingec, Metin | |
dc.contributor.author | Canakci, Hümeyra | |
dc.contributor.author | Sezer, Ufuk | |
dc.date.accessioned | 2023-05-16T16:06:37Z | |
dc.date.available | 2023-05-16T16:06:37Z | |
dc.date.issued | 2017-12-31T21:00:00Z | |
dc.description.abstract | In patients with polycystic ovary syndrome (PCOS), chronic periodontitis (CP) contributed to increased oxidative stress (OS), owing to an increase in serum and salivary 8-hydroxy-2'-deoxyguanosine (8-OHdG) and malondialdehyde (MDA) levels and a decrease in serum total antioxidant status (TAS) levels. The aim of the present study is to investigate salivary and serum 8-OHdG and MDA levels as well as total antioxidant status (TAS) in females with CP and PCOS compared with healthy females. | |
dc.description.abstract | Four groups, each consisting of 22 individuals, were: 1) women with both PCOS and CP (PCOSCP); 2) systemically healthy women with CP; 3) periodontally healthy women with PCOS (PCOSPH); and 4) periodontally and systemically healthy women (PH). Demographic and clinical periodontal parameters were measured. Oxidative parameters were evaluated in serum and salivary samples. | |
dc.description.abstract | Salivary 8-OHdG levels in the PCOSCP and CP groups were statistically higher than those in both the PCOSPH and the PH groups (P < 0.05). There was no statistical difference between the PCOSCP, CP, and PCOSPH groups with regard to salivary MDA and TAS levels (P > 0.05). Highest serum 8-OHdG and MDA levels and lowest serum TAS levels were seen in the PCOSCP group (P < 0.05). Serum 8-OHdG and MDA levels in the PCOSPH group were higher than those in both systemically healthy groups (PH and CP) (P < 0.05). Salivary TAS levels were highest (P < 0.05) in the PH group. There was no statistical difference between the CP and PCOSPH groups, but serum TAS levels were lower than those in the PH group (P < 0.05). | |
dc.description.abstract | CP, which led to an increase in serum and salivary 8-OHdG and MDA levels and a decrease in serum TAS levels in patients with PCOS, contributed to increased OS. This effect was more prominent in serum levels than in salivary levels. | |
dc.identifier.pubmed | 28844187 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12645/38087 | |
dc.language.iso | en | |
dc.subject | Chronic periodontitis | |
dc.subject | malondialdehyde | |
dc.subject | oxidative stress | |
dc.subject | polycystic ovary syndrome | |
dc.title | Evaluation of oxidative status in patients with chronic periodontitis and polycystic ovary syndrome: A cross-sectional study. | |
dspace.entity.type | Publication | |
local.indexed.at | PubMed |