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Comparison of clinical features of COVID-19 infection in children with asthma and their healthy peers

dc.contributor.authorNursoy, Mustafa A
dc.contributor.authorBülbül, Lida
dc.contributor.authorYazıcı, Mebrure
dc.contributor.authorAltınel, Nazan
dc.contributor.authorUstabaş Kahraman, Feyza
dc.contributor.authorÖzkul Sağlam, Neslihan
dc.contributor.authorBursal Duramaz, Burcu
dc.contributor.authorTürel, Özden
dc.contributor.authorÇakır, Erkan
dc.contributor.institutionauthorUSTABAŞ KAHRAMAN, FEYZA
dc.contributor.institutionauthorTÜREL, ÖZDEN
dc.contributor.institutionauthorÇAKIR, ERKAN
dc.date.accessioned2022-05-05T20:59:19Z
dc.date.available2022-05-05T20:59:19Z
dc.date.issued2022-04-23T00:00:00Z
dc.description.abstractAim: We aimed to assess the impact of COVID-19 on asthma exacerbations and to compare the severity of symptoms of SARS-CoV-2 infection of asthmatic children with those of healthy children. Methods: The clinical course of COVID-19 was compared among 89 children with asthma and 84 healthy children with age- and gender-matched. Demographic factors, severity of asthma, duration of asthma, presence of atopy, type of treatment, and compliance to treatment in asthmatic children on clinical course of infection and to determine the risk factors for severe course for asthma exacerbation during COVID-19 were evaluated retrospectively. Demographic characteristics, clinical symptoms, duration of complaints, and hospitalization rates were statistically compared between the two groups. Results: Both groups had similar rates of symptomatic disease, hospitalization, and duration of fever. Among children with asthma mean age was 10.3 years, 59.6% were male, and 84.3% had mild asthma. Dyspnea was more prevalent in asthmatic children (p:0.012), but other clinical findings were not different from those of healthy controls. 12.4% (n:11) of asthmatic children had asthma exacerbation, 2.2% (n:2) of them were hospitalized; one (1.1%) of which was due to asthma exacerbation. Conclusion: The course of COVID-19 in patients with mild to moderate asthma, who were followed up regularly and who were compliant with their treatment, was similar to their healthy peers. Since there was no severe asthma case in our study, the results could not have been generalized to all asthmatic patients. Further comprehensive and multicenter studies are required in pediatric population.
dc.identifier.doi10.1002/ppul.25937
dc.identifier.pubmed35460332
dc.identifier.scopus85129340757
dc.identifier.urihttp://hdl.handle.net/20.500.12645/30569
dc.identifier.wosWOS:000789878100001
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectasthma
dc.subjectchildren
dc.titleComparison of clinical features of COVID-19 infection in children with asthma and their healthy peers
dc.typeArticle
dspace.entity.typePublication
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local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
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