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Effects of Recombinant Activated Protein C Derived From Drotrecogin-Alpha on Bleomycin-Induced Pulmonary Fibrosis in Rats Compared with Methyl-Prednisolone

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Yildiz, Kadir
Iraz, Mustafa
ŞAMDANCI, EMİNE
ÖZEROL, ELİF
KUKU, İRFAN
AYTEMUR, ZEYNEP AYFER
HACIEVLİYAGİL, SÜLEYMAN SAVAŞ

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OBJECTIVE: In this study, we aimed to test the preventive effects of intraperitoneally administered drotrecogin alpha which is derived from activated protein C (APC), on bleomycin-induced pulmonary fibrosis in rats, and to compare the effects of APC with the effects of methyl-prednisolone, a traditional therapy.

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Yildiz K., Iraz M., ŞAMDANCI E., ÖZEROL E., KUKU İ., AYTEMUR Z. A. , HACIEVLİYAGİL S. S. , -Effects of Recombinant Activated Protein C Derived From Drotrecogin-Alpha on Bleomycin-Induced Pulmonary Fibrosis in Rats Compared with Methyl-Prednisolone-, TURKISH THORACIC JOURNAL, cilt.14, ss.48-52, 2013

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