Traditional Herbs in Anatolian Medicine for Rosacea: A Basis for Non-Steroidal Magistral Therapy

Abstract

Rosacea is a chronic inflammatory disorder with a prevalence reported between less than 1% and 22% across populations, increasing annually. In the context of rosacea management, numerous aspects of the condition’s pathophysiology remain insufficiently understood. Despite the availability of various topical and oral treatments and laser therapies for rosacea, their limitations, common adverse effects, and high costs frequently lead to premature discontinuation, driving greater interest in plant-based formulations among both clinicians and patients. Consequently, herbal products containing natural ingredients are increasingly preferred over synthetic alternatives, owing to their multiple benefits and lower frequency and severity of side effects. This review emphasizes that a range of herbal extracts and oils, traditionally used in Anatolian medicine which is supported by literature mainly for their anti-inflammatory, antioxidant, antimicrobial, and anti-erythematous effects, possess significant potential in managing rosacea. Drawing on recent preclinical and clinical studies, Our study outlines the mechanisms by which various phytochemicals alleviate the clinical symptoms of rosacea, thereby enhancing understanding of the therapeutic potential of plant-based products and guiding future researches.