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Effects of boric acid on bone formation after maxillary sinus floor augmentation in rabbits

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dc.contributor.authorUlu, Murat
dc.contributor.authorKÜTÜK, NÜKHET
dc.contributor.authorCicik, Muhammet Furkan
dc.contributor.authorBİLGE, SUHEYB
dc.contributor.authorAkcay, Huseyin
dc.contributor.authorSAYĞILI, Suna
dc.contributor.authorTuglu, Mehmet Ibrahim
dc.contributor.authorALKAN, ALPER
dc.contributor.institutionauthorKÜTÜK, NÜKHET
dc.contributor.institutionauthorALKAN, ALPER
dc.date.accessioned2019-12-29T20:59:39Z
dc.date.available2019-12-29T20:59:39Z
dc.date.issued2018-12-01
dc.description.abstractPurposeAugmentation of the maxillary sinus floor with bone grafting is commonly used for successful treatment of edentulous posterior maxilla with dental implants, and it is essential to maintain good bone volume and quality for long-term success of dental implants. The aim of this experimental study was to investigate the local and systemic effects of boric acid on new bone formation after maxillary sinus floor augmentation (MSFA).Materials and methodsTwenty-four male, New Zealand rabbits were randomly divided into three groups with eight rabbits each, and bilateral MSFA was performed in each animal. An autogenous bone/xenograft mixture was used to augment the maxillary sinuses in each group. Group 1 was determined as control with no additional materials, whereas 3mg/kg boric acid (BA) was added to the mixture in group 2, and 3mg/kg boric acid solution added to drinking water daily in group 3.ResultsThe animals were sacrificed and also histologic, histomorphometric, and immunnohistochemical analyses were performed at weeks 4 and 8. At week 4, bone regeneration was better in the local BA group than in the control and systemic BA groups (p0.05).ConclusionSignificant higher new bone formation was revealed by BA at early healing especially with local application. BA may be a therapeutic option for improving the bone regeneration.
dc.identifier.citationUlu M., KÜTÜK N., Cicik M. F. , BİLGE S., Akcay H., SAYĞILI S., Tuglu M. I. , ALKAN A., -Effects of boric acid on bone formation after maxillary sinus floor augmentation in rabbits-, ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG, cilt.22, ss.443-450, 2018
dc.identifier.doi10.1007/s10006-018-0729-3
dc.identifier.pubmed30345483
dc.identifier.scopus85055719586
dc.identifier.urihttps://hdl.handle.net/20.500.12645/11112
dc.identifier.wosWOS:000449525900012
dc.titleEffects of boric acid on bone formation after maxillary sinus floor augmentation in rabbits
dc.typeArticle
dspace.entity.typePublication
local.avesis.idb4a8e90e-ee9d-4b9f-ae7a-10deefd074f3
local.publication.isinternational1
relation.isAuthorOfPublication908c31f8-027f-44c3-9992-1f8b42ac3367
relation.isAuthorOfPublicationf621b6f2-1415-4076-b3a2-78835a8712bd
relation.isAuthorOfPublication.latestForDiscoveryf621b6f2-1415-4076-b3a2-78835a8712bd
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