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Daytime variations of tear osmolarity measurement in dry eye patients Kuru göz hastalari{dotless}nda gözyaşi{dotless} osmolarite ölçümünün gün İçi deǧişiklikleri

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dc.contributor.authorYiǧit, Ulviye
dc.contributor.authorEvcimen, Yusuf
dc.contributor.authorKirik, FURKAN
dc.contributor.authorAǧaçhan, Ahmet
dc.contributor.institutionauthorKIRIK, FURKAN
dc.date.accessioned2021-08-31T20:59:29Z
dc.date.available2021-08-31T20:59:29Z
dc.date.issued2013-01-01T00:00:00Z
dc.description.abstractPurpose: We have targeted primarily to show the variations of tear osmolarity during the daytime period in subjects with dry eyes and non-dry eyes and, secondarily, to evaluate the relationship of these variations with Schirmer-s test and break-up time (BUT). Material and Method: Twenty newly diagnosed dry eye patients and 20 healthy voluntary subjects with similar age and gender were included in this prospective study. In addition to the full ophthalmic examination, Schirmer-s test and BUT test were applied to all participants. Tear osmolarity measurements were done after pre-examination but in different day. The measurements were registered with TearLab Osmolarity System (TearLab Corporation, San Diego, CA, USA) every 3 hours within 8:00 AM and 5:00 PM. The results were evaluated statistically. Results: No statistically significant difference was found between the mean age and gender of dry eye syndrome (DES) and control groups (p>0.05). The mean measurements of Schirmer-s test and BUT in the DES group were statistically significantly lower than those in the control group (p=0.0001). The mean measurements of tear osmolarity at 8:00 AM, 11:00 AM, 2:00 PM, and 5:00 PM in the DES group were statistically significantly higher than those in the control group (p=0.001, p=0.0001). No statistically significant difference in tear osmolarity at 8:00 AM, 11: 00 AM, 2:00 PM, and 5:00 PM was found between the groups, and within DES and control groups (p>0.05). Discussion: We did not determine significant change in daytime variations of the tear osmolarity in dry eye patients and healthy subjects. As a secondary result, we can conclude that there is no difference among tear osmolarity, Shirmer-s and BUT tests in the diagnosis of DES.
dc.identifier.citationYiǧit U., Evcimen Y., Kirik F., Aǧaçhan A., -Daytime variations of tear osmolarity measurement in dry eye patients Kuru göz hastalari{dotless}nda gözyaşi{dotless} osmolarite ölçümünün gün İçi deǧişiklikleri-, Turk Oftalmoloiji Dergisi, cilt.43, sa.6, ss.437-441, 2013
dc.identifier.doi10.4274/tjo.20092
dc.identifier.scopus84894551779
dc.identifier.urihttp://hdl.handle.net/20.500.12645/29326
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleDaytime variations of tear osmolarity measurement in dry eye patients Kuru göz hastalari{dotless}nda gözyaşi{dotless} osmolarite ölçümünün gün İçi deǧişiklikleri
dc.typeArticle
dspace.entity.typePublication
local.avesis.idddcbe48b-231e-4bdc-bfc1-f65b22d9cb26
local.publication.isinternational1
relation.isAuthorOfPublicatione21e3ef7-b620-452f-a470-b5938d67d233
relation.isAuthorOfPublication.latestForDiscoverye21e3ef7-b620-452f-a470-b5938d67d233
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