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Mortality markers in nosocomial Klebsiella pneumoniae bloodstream infection

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dc.contributor.authorDurdu, BÜLENT
dc.contributor.authorHakyemez, Ismail Necati
dc.contributor.authorBOLUKÇU, SİBEL
dc.contributor.authorOKAY, GÜLAY
dc.contributor.authorASLAN, Turan
dc.contributor.institutionauthorDURDU, BÜLENT
dc.contributor.institutionauthorHAKYEMEZ, İSMAİL NECATİ
dc.contributor.institutionauthorBOLUKÇU, SİBEL
dc.contributor.institutionauthorOKAY, GÜLAY
dc.contributor.institutionauthorSÜMBÜL, BİLGE
dc.date.accessioned2019-10-05T21:23:34Z
dc.date.available2019-10-05T21:23:34Z
dc.date.issued2016-10-28
dc.description.abstractPurpose: Klebsiella pneumoniae is the most common endogen agent for nosocomial infections. In this study, mortality markers were investigated in patients with nosocomial K. pneumoniae blood stream infection (NKp BSI). Methods: The characteristics of patients >16 years who had NKp BSI diagnosis by daily active surveillance between January 2012 and January 2016 were retrospectively evaluated. Patients who died until 28th day of the clinical follow up and those who survived until this time were statistically compared in terms of various risk factors. Results: One hundred ninety patients were included into the study. Mortality rate was 47.9%, carbapenem resistance was 43.2%. Statistical analysis have shown that in presence of post-NKp BSI sepsis, septic shock, following in intensive care unit (ICU), meropenem resistance, kidney failure, NKp BSI secondary to pneumonia, use of invasive instruments such as central venous catheter (CVC), urinary catheter (UC) and mechanical ventilator (MV), colostomy, transfusion and hemodialysis mortality was significantly higher. In patients admitted into the hospital for neurological disorders, pancreaticobiliary tract (PBT) diseases and patients who have undergone endoscopic retrograde cholangiopancreatography (ERCP) and patients in whom NKp BSI secondary to PBT infection mortality rate was lower. Conclusions: Sepsis, septic shock, clinical conditions requiring ICU treatment and meropenem resistance increase mortality rates in NKp BSI significantly. Mortality was higher also in patients with NKp BSI secondary to pneumonia, in kidney failure and when invasive instruments were used. On the other hand, in patients who were admitted to the hospital for neurological disorders and PBT diseases mortality rate was lower.en
dc.identifier10.1016/s0031-9422(00)97086-9
dc.identifier.citationDurdu B., Hakyemez I. N. , BOLUKÇU S., OKAY G., GULTEPE B., ASLAN T., -Mortality markers in nosocomial Klebsiella pneumoniae bloodstream infection-, SPRINGERPLUS, cilt.5, 2016
dc.identifier.doi10.1186/s40064-016-3580-8
dc.identifier.pubmed27843749
dc.identifier.scopus84993977991
dc.identifier.urihttps://hdl.handle.net/20.500.12645/7187
dc.identifier.wosWOS:000391814300007
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleMortality markers in nosocomial Klebsiella pneumoniae bloodstream infection
dc.typeArticle
dspace.entity.typePublication
local.article.journalnamePHYTOCHEMISTRY
local.avesis.idb312350a-e419-48dd-9881-55255c211c2a
local.avesis.response7063
local.publication.isinternational1
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relation.isAuthorOfPublication.latestForDiscovery34a9d344-3a58-4f83-864a-5a5c664557bd
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