Publication:
Dosimetric comparison of helical tomotherapy, intensity-modulated radiation therapy, volumetric-modulated arc therapy, and 3-dimensional conformal therapy for the treatment of T1N0 glottic cancer

Simple item page
dc.contributor.authorEkici, Kemal
dc.contributor.authorPepele, Eda K.
dc.contributor.authorYaprak, Bahaddin
dc.contributor.authorTernelli, Oztun
dc.contributor.authorEraslan, Aysun F.
dc.contributor.authorKucuk, Nadir
dc.contributor.authorAltinok, Ayse Y.
dc.contributor.authorSut, Pelin A.
dc.contributor.authorALPAK, Ozlem D.
dc.contributor.authorÇOLAK, CEMİL
dc.contributor.authorMayadagli, ALPASLAN
dc.contributor.institutionauthorALTINOK SÜT, PELİN
dc.contributor.institutionauthorMAYADAĞLI, ALPASLAN
dc.date.accessioned2020-10-29T22:42:12Z
dc.date.available2020-10-29T22:42:12Z
dc.date.issued2016-12-01T00:00:00Z
dc.description.abstractVarious radiotherapy planning methods for T1N0 laryngeal cancer have been proposed to decrease normal tissue toxicity. We compare helical tomotherapy (HT), linac-based intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), and 3-D conformal radiotherapy (3D-CRT) techniques for T1N0 laryngeal cancer. Overall, 10 patients with T1N0 laryngeal cancer were selected and evaluated. Furthermore, 10 radiotherapy treatment plans have been created for all 10 patients, including HT, IMRT, VMAT, and 3D-CRT. IMRT, VMAT, and HT plans vs 3D-CRT plans consistently provided superior planning target volume (PTV) coverage. Similar target coverage was observed between the 3 IMRT modalities. Compared with 3D-CRT, IMRT, HT, and VMAT significantly reduced the mean dose to the carotid arteries. VMAT resulted in the lowest mean dose to the submandibular and thyroid glands. Compared with 3D-CRT, IMRT, HT, and VMAT significantly increased the maximum dose to the spinal cord It was observed that the 3 IMRT modalities studied showed superior target coverage with less variation between each plan in comparison with 3D-CRT. The 3D-CRT plans performed better at the Dmax of the spinal cord. Clinical investigation is warranted to determine if these treatment approaches would translate into a reduction in radiation therapy-induced toxicities. (C) 2016 American Association of Medical Dosimetrists.
dc.identifier.citationEkici K., Pepele E. K. , Yaprak B., Ternelli O., Eraslan A. F. , Kucuk N., Altinok A. Y. , Sut P. A. , ALPAK O. D. , ÇOLAK C., et al., -Dosimetric comparison of helical tomotherapy, intensity-modulated radiation therapy, volumetric-modulated arc therapy, and 3-dimensional conformal therapy for the treatment of T1N0 glottic cancer-, Medical Dosimetry, cilt.41, ss.329-333, 2016
dc.identifier.doi10.1016/j.meddos.2016.08.002
dc.identifier.pubmed27765542
dc.identifier.scopus85006069953
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26698
dc.identifier.wosWOS:000389011500012
dc.titleDosimetric comparison of helical tomotherapy, intensity-modulated radiation therapy, volumetric-modulated arc therapy, and 3-dimensional conformal therapy for the treatment of T1N0 glottic cancer
dc.typeArticle
dspace.entity.typePublication
local.avesis.idbc8c7664-43eb-4bec-ba57-b5f65390b5f7
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication81a5e774-a7ba-49dd-8a3f-d42d2d30f19a
relation.isAuthorOfPublication3f87e3db-e55d-48a8-b15f-c4f4d75c7839
relation.isAuthorOfPublication.latestForDiscovery81a5e774-a7ba-49dd-8a3f-d42d2d30f19a
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
Files
Collections
Yayınlar - Eserler