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The effect of topical ethanol extract of Cotinus coggygria Scop. on cutaneous wound healing in rats

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dc.contributor.authorAKSOY, HALİL
dc.contributor.authorSANCAR, MESUT
dc.contributor.authorŞEN, ALİ
dc.contributor.authorOKUYAN, BETÜL
dc.contributor.authorBİTİŞ, LEYLA
dc.contributor.authorUras, Fikriye
dc.contributor.authorAKAKIN, DİLEK
dc.contributor.authorCevik, Ozge
dc.contributor.authorKultur, Sukran
dc.contributor.authorIzzettin, Fikret Vehbi
dc.contributor.institutionauthorİZZETTİN, FIKRET VEHBI
dc.date.accessioned2020-10-30T00:13:26Z
dc.date.available2020-10-30T00:13:26Z
dc.date.issued2016-01-01T00:00:00Z
dc.description.abstractThe aim of this study is to determine the cutaneous wound healing effects of the ethanol extract of Cotinus coggygria leaves in rats by excision wound model to provide scientific evidence for the traditional use of C. coggygria Scop. The levels of malondialdehyde, catalase, superoxide dismutase, glutathione and hydroxyproline were investigated in wound tissues. Histopathological examination was also performed. The hydroxyproline content of the granulation tissue and the glutathione levels were both significantly higher in the treatment group than in the control group (p < 0.05 for both); while the malondialdehyde levels were significantly lower in the treatment group (p < 0.05). These results were supported with histological results. The ethanol extract of C. coggygria Scop could be considered as an effective agent in wound healing in accordance with its traditional use.
dc.identifier.citationAKSOY H., SANCAR M., ŞEN A., OKUYAN B., BİTİŞ L., Uras F., AKAKIN D., Cevik O., Kultur S., Izzettin F. V. , -The effect of topical ethanol extract of Cotinus coggygria Scop. on cutaneous wound healing in rats-, NATURAL PRODUCT RESEARCH, cilt.30, ss.452-455, 2016
dc.identifier.doi10.1080/14786419.2015.1019349
dc.identifier.scopus84955210634
dc.identifier.urihttp://hdl.handle.net/20.500.12645/27131
dc.identifier.wosWOS:000375841100014
dc.titleThe effect of topical ethanol extract of Cotinus coggygria Scop. on cutaneous wound healing in rats
dc.typeArticle
dspace.entity.typePublication
local.avesis.idecbacb41-b8ad-40af-a6dc-d159b3e868a9
local.publication.isinternational1
relation.isAuthorOfPublicationcc4fb95b-daac-4065-9eea-9b57f6b44654
relation.isAuthorOfPublication.latestForDiscoverycc4fb95b-daac-4065-9eea-9b57f6b44654
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