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Long Term Benefits of Post-surgical Adjuvant Radiotherapy Among Sub-population of Patients with Stage IB Grade 2 Endometrial Cancer

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dc.contributor.authorKocak, Mihriban
dc.contributor.authorEren, Makbule
dc.contributor.authorNaki, Murat M.
dc.contributor.authorAksu, Atinc
dc.contributor.authorCelik, Hasniye
dc.contributor.authorOzkan, Alper
dc.contributor.authorMayadagli, Alpaslan
dc.contributor.authorUnal, Orhan
dc.contributor.institutionauthorMAYADAĞLI, ALPASLAN
dc.date.accessioned2021-04-15T20:59:30Z
dc.date.available2021-04-15T20:59:30Z
dc.date.issued2011-01-01T00:00:00Z
dc.description.abstractPresent study was designed to evaluate potential risks and benefits of adjuvant radiotherapy in selected patients with intermediate-risk endometrial cancer. A total of 100 patients with stage IB grade II endometrial cancer followed up in Radiation Oncology Clinic at Dr. Lutfi Kirdar Training and Research Hospital were evaluated retrospectively to determine the influence of postsurgical adjuvant radiotherapy on disease-free survival, local recurrences and locally-relaps free survival. Side effects related to adjuvant radiotherapy were also evaluated. Forty-seven (47%) patients were determined to undergo total abdominal hysterectomy + bilateral salphingo-oopherectomy and 53 (53%) patients, total abdominal hysterectomy + bilateral salphingo-oopherectomy + pelvic lymph node dissection. Postsurgical adjuvant radiotherapy was administered in 77 patients (77%), while the surgery was the sole medical intervention for 23 patients (23%). The median follow-up period was 40.5 months (range: 6-139) Five-year disease-free survival (96.6% vs. 80.5%; p<0.01) and local control (98.6% vs. 80.5%; p<0.05) were better in patients who were administered postoperative radiotherapy compared to patients without postoperative radiotherapy.
dc.identifier.citationKocak M., Eren M., Naki M. M. , Aksu A., Celik H., Ozkan A., Mayadagli A., Unal O., -Long Term Benefits of Post-surgical Adjuvant Radiotherapy Among Sub-population of Patients with Stage IB Grade 2 Endometrial Cancer-, UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.21, sa.2, ss.71-79, 2011
dc.identifier.doi10.4999/uhod.09133
dc.identifier.scopus79959670487
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28770
dc.identifier.wosWOS:000292413500002
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleLong Term Benefits of Post-surgical Adjuvant Radiotherapy Among Sub-population of Patients with Stage IB Grade 2 Endometrial Cancer
dc.typeArticle
dspace.entity.typePublication
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local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
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relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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