Publication: The role of midkine in the inflammatory process and its correlation with other inflammatory markers in renal transplant recipients
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2016-06-01T00:00:00Z
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Uzun, Sami
Kaya, Burcu
Celik, Kenan
Behlul, Ahmet
Ozkan, Oktay
Kuvvet, Melike
Doventas, Yasemin Erdogan
Gursu, Meltem
Karadag, Serhat
Sumnu, Abdullah
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Abstract
Background: Midkine (MK), which is expressed in the proximal tubular epithelial cells of the kidney, is thought to have a role in the pathophysiology of inflammation-related renal diseases. Both immunological and nonimmunological mechanisms may affect renal functions negatively during the early and late post-transplantation periods. We aimed in our study to evaluate the relationship of MK with clinical findings and inflammatory markers, including high sensitivity C-reactive protein (hs-CRP), interleukin (IL-6) and tumor necrosis factor (TNF-alpha) in the pretransplant and post-transplant period.
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Uzun S., Kaya B., Celik K., Behlul A., Ozkan O., Kuvvet M., Doventas Y. E. , Gursu M., Karadag S., Sumnu A., et al., -The role of midkine in the inflammatory process and its correlation with other inflammatory markers in renal transplant recipients-, INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, cilt.39, ss.277-281, 2016