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Corneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: a four-year comparative study

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dc.contributor.authorKUBALOGLU, A
dc.contributor.authorKoytak, A
dc.contributor.authorSARI, ES
dc.contributor.authorAKYOL, S
dc.contributor.authorKURNAZ, E
dc.contributor.authorOZERTURK, Y
dc.contributor.institutionauthorKOYTAK, İBRAHİM ARİF
dc.date.accessioned2020-10-29T14:02:59Z
dc.date.available2020-10-29T14:02:59Z
dc.date.issued2012-01-01T00:00:00Z
dc.description.abstractPurpose: To compare the status of corneal endothelium and central corneal thickness within the first four postoperative years after deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus. Materials and Methods: Thirty-nine eyes (Group A) which had PK and 44 eyes (Group B) which had DALK for the treatment of keratoconus were included in this retrospective study. The endothelial cell density (ECD), the mean endothelial cell area and the coefficient of variation of cell area were assessed with a non-contact specular microscope, and the central corneal thickness (CCT) was measured with an ultrasound pachymeter. Results: Mean ECD loss rate at two years was 36.24% in Group A and 18.12% in Group B (P<0.001). Mean ECD loss rate at four years was 47.82% in Group A and 21.62% in Group B (P<0.001). Mean annual ECD loss rate was calculated 14.12% per year in Group A and 5.78% per year in Group B. In the PK group, increase in mean CCT was 15.60% in two years and 15.03% in four years, while in the DALK group, mean CCT increased by 8.05% in two years and 9.31% in four years. Conclusions: As the majority of ectatic disorders such as keratoconus occur in young people, long-term endothelial cell survival following treatment with keratoplasty is essential for the long-term visual ability. Our finding that corneal endothelial cell loss in the DALK group occurs at a slower rate than in the PK group suggests DALK as a safer alternative to PK in these selected patients.
dc.identifier.citationKUBALOGLU A., Koytak A., SARI E., AKYOL S., KURNAZ E., OZERTURK Y., -Corneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: a four-year comparative study.-, Indian journal of ophthalmology, cilt.60, ss.35-40, 2012
dc.identifier.doi10.4103/0301-4738.90490
dc.identifier.pubmed22218243
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25219
dc.identifier.wosWOS:000315668300007
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectpenetrating keratoplasty
dc.titleCorneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: a four-year comparative study
dc.typeArticle
dspace.entity.typePublication
local.avesis.id19aad81e-239c-457d-b3fc-cf8d5f833913
local.publication.isinternational1
relation.isAuthorOfPublicationad20e4da-e310-4188-9b32-8fb51734eb5f
relation.isAuthorOfPublication.latestForDiscoveryad20e4da-e310-4188-9b32-8fb51734eb5f
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Corneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: A four-year comparative study
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