Publication:
Aurone Scaffold and Structural Analogues for the Development of Monoamine Oxidase (MAO) Inhibitors

Simple item page
dc.contributor.authorGuglielmi P.
dc.contributor.authorPontecorvi V.
dc.contributor.authorAkdemir A.
dc.contributor.institutionauthorAKDEMİR, ATİLLA
dc.date.accessioned2023-01-08T22:40:37Z
dc.date.available2023-01-08T22:40:37Z
dc.date.issued2022-12-01
dc.description.abstractMedicinal chemists around the world have been inspired by nature and have successfully extracted chemicals from plants. Research on enzymatic modifications of naturally occurring compounds has played a critical role in the search for biologically active molecules to treat diseases. This book explores compounds of interest to researchers and clinicians. It presents a comprehensive analysis about the medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) of different compounds. Each chapter brings contributions from known scientists explaining experimental results which can be translated into clinical practice. Each chapter follows a specific format for a phytochemical agent with common chemical features: • General background on the (phyto)chemistry of the scaffold • General background on the pharmacological profile of the scaffold • A Description of the proposed derivatives and their advantages with respect to the parent compounds (emphasizing the synthetic approaches and structure-activity relationships) • In silico analysis of the crucial interactions with the biological target • Clinical studies and patent survey (if available) on the new and proposed structures The objective of this book set is to fulfil gaps in currently acquired knowledge with information from the recent years. It serves as a guide for academic and professional researchers and clinicians.
dc.identifier.citationGuglielmi P., Pontecorvi V., Akdemir A., Aurone Scaffold and Structural Analogues for the Development of Monoamine Oxidase (MAO) Inhibitors, "Flavonoids and Phenolics. Medicinal Chemistry Lessons From Nature", Simone Carradori, Editör, Bentham Science Publisher, London, ss.272-297, 2022
dc.identifier.endpage297
dc.identifier.isbn978-981-5079-10-4
dc.identifier.startpage272
dc.identifier.urihttps://www.eurekaselect.com/ebook_volume/3439
dc.identifier.urihttps://hdl.handle.net/20.500.12645/34801
dc.publisherBentham Science Publisher
dc.relation.ispartofFlavonoids and Phenolics. Medicinal Chemistry Lessons From Nature
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEczacılık
dc.subjectMeslek Bilimleri
dc.subjectFarmakoloji
dc.subjectFarmasötik Kimya
dc.subjectSağlık Bilimleri
dc.subjectPharmacology and Therapeutics
dc.subjectProfessional Sciences
dc.subjectPharmacology
dc.subjectPharmaceutical Chemistry
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectClinical Medicine (MED)
dc.subjectLife Sciences (LIFE)
dc.subjectPHARMACOLOGY & TOXICOLOGY
dc.subjectPHARMACOLOGY & PHARMACY
dc.subjectFarmakoloji, Toksikoloji ve Eczacılık (çeşitli)
dc.subjectGenel Farmakoloji, Toksikoloji ve Eczacılık
dc.subjectFarmakoloji (tıbbi)
dc.subjectİlaç Rehberleri
dc.subjectYaşam Bilimleri
dc.subjectPharmacy
dc.subjectPharmacology, Toxicology and Pharmaceutics (miscellaneous)
dc.subjectGeneral Pharmacology, Toxicology and Pharmaceutics
dc.subjectPharmacology (medical)
dc.subjectDrug Guides
dc.subjectLife Sciences
dc.titleAurone Scaffold and Structural Analogues for the Development of Monoamine Oxidase (MAO) Inhibitors
dc.typebookPart
dspace.entity.typePublication
local.avesis.id373345e5-5f01-42f6-a634-5fea57c54147
relation.isAuthorOfPublication19bc513a-c695-4e72-ba1d-83b8d6c574c8
relation.isAuthorOfPublication.latestForDiscovery19bc513a-c695-4e72-ba1d-83b8d6c574c8
Files
Collections
Yayınlar - Eserler