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Determination of Apigenin in Cosmetics Containing Chamomile by High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV)

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dc.contributor.authorSerim E.
dc.contributor.authorCeylan B.
dc.contributor.authorKepekci Tekkeli S. E.
dc.contributor.institutionauthorTEKKELİ, ŞERİFE EVRİM
dc.date.accessioned2023-01-08T22:59:22Z
dc.date.available2023-01-08T22:59:22Z
dc.date.issued2022-01-01
dc.description.abstract© 2022 Taylor & Francis Group, LLC.A simple, rapid, and precise high performance liquid chromatography (HPLC) method was developed to determine the flavonoid apigenin in cosmetic products containing chamomile extracts. A C18 column was used as stationary phase and 70:30 ethanol:water was used as mobile phase with a 1 mL/min flow rate and isocratic elution. The temperature was stabilized at 25 °C during the separation. The injection volume was 50 μL. The apigenin peak was eluted at 4.15 ± 0.4 min. The method was validated according to International Conference on Harmonisation (ICH) criteria in terms of linearity, limit of detection, limit of quantitation, selectivity, sensitivity, robustness, accuracy, and precision. The limits of detection and quantitation were 0.060 and 0.2 μg/mL respectively. The linear range was from 0.2 to 20 μg/mL. The relative standard deviation values for intraday and interday analyses were less than 1.64%. The developed procedure was applied to the analysis of various cosmetic products. It is expected that the method is suitable for routine analysis, quality control and standardization of cosmetic products for apigenin.
dc.identifier.citationSerim E., Ceylan B., Kepekci Tekkeli S. E., "Determination of Apigenin in Cosmetics Containing Chamomile by High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV)", Analytical Letters, 2022
dc.identifier.doi10.1080/00032719.2022.2155180
dc.identifier.issn0003-2719
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85144232809&origin=inward
dc.identifier.urihttps://hdl.handle.net/20.500.12645/34925
dc.relation.ispartofAnalytical Letters
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectKimya
dc.subjectAnalitik Kimya
dc.subjectFizikokimya
dc.subjectElektrokimya
dc.subjectSpektroskopi
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyokimya
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectLife Sciences
dc.subjectMolecular Biology and Genetics
dc.subjectCytogenetic
dc.subjectChemistry
dc.subjectAnalytical Chemistry
dc.subjectPhysical Chemistry
dc.subjectElectrochemistry
dc.subjectSpectroscopy
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectBiochemistry
dc.subjectNatural Sciences
dc.subjectTemel Bilimler (SCI)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectBiyoloji ve Biyokimya
dc.subjectKİMYA, ANALİTİK
dc.subjectSPEKTROSKOPİ
dc.subjectELEKTROKİMYA
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectNatural Sciences (SCI)
dc.subjectLife Sciences (LIFE)
dc.subjectCHEMISTRY
dc.subjectBIOLOGY & BIOCHEMISTRY
dc.subjectMOLECULAR BIOLOGY & GENETICS
dc.subjectCHEMISTRY, ANALYTICAL
dc.subjectSPECTROSCOPY
dc.subjectELECTROCHEMISTRY
dc.subjectBIOCHEMISTRY & MOLECULAR BIOLOGY
dc.subjectFizik Bilimleri
dc.subjectKlinik Biyokimya
dc.subjectBiyokimya (tıbbi)
dc.subjectPhysical Sciences
dc.subjectClinical Biochemistry
dc.subjectBiochemistry (medical)
dc.subjectApigenin
dc.subjectchamomile
dc.subjectflavonoids
dc.subjecthigh-performance liquid chromatography with ultraviolet detection (HPLC-UV)
dc.titleDetermination of Apigenin in Cosmetics Containing Chamomile by High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV)
dc.typearticle
dspace.entity.typePublication
local.avesis.idec2200aa-b477-488b-9e78-760d118ed202
relation.isAuthorOfPublication837d5047-762e-43db-b252-9f3d1399378f
relation.isAuthorOfPublication.latestForDiscovery837d5047-762e-43db-b252-9f3d1399378f
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