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Abbreviated and Standard Breast MRI in Neoadjuvant Chemotherapy Response Evaluation: A Comparative Study.

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dc.contributor.authorYirgin, Inci Kizildag
dc.contributor.authorEngin, Gulgun
dc.contributor.authorYildiz, Şeyma
dc.contributor.authorAydin, Esra Cureoglu
dc.contributor.authorKaranlik, Hasan
dc.contributor.authorCabioglu, Neslihan
dc.contributor.authorTukenmez, Mustafa
dc.contributor.authorEmiroglu, Selman
dc.contributor.authorOnder, Semen
dc.contributor.authorYildiz, Sevda Ozel
dc.contributor.authorYavuz, Ekrem
dc.contributor.authorSaip, Pınar
dc.contributor.authorAydiner, Adnan
dc.contributor.authorIgci, Abdullah
dc.contributor.authorMuslumanoglu, Mahmut
dc.date.accessioned2023-05-18T21:23:28Z
dc.date.available2023-05-18T21:23:28Z
dc.description.abstractThis study aims to investigate the efficacy of abbreviated breast magnetic resonance imaging (MRI) in neoadjuvant chemotherapy (NAC) response evaluation.
dc.description.abstractMR images of 50 locally advanced breast cancer patients who underwent standard protocol (SP) breast MRI before and after NAC were re-evaluated retrospectively. Abbreviated protocol (AP) was obtained by extracting images from SP and then evaluating them in a separate session. Protocols were compared with the histological findings after surgery as the reference standard.
dc.description.abstractA statistically significant difference was found between the two protocols in response evaluation by the McNemar test (p=0.018). However, the Kappa value was 0.62 (p<0.001), which indicates substantial agreement. No statistically significant differences were found between the two protocols (AP and SP) and pathological results in the McNemar test (p=0.12, p=0.60, respectively). Kappa values were 0.48 (p<0.001) and 0.60 (p<0.001), respectively, which indicates moderate agreement for both protocols with higher values by SP evaluation. The residual maximum median diameters were smaller than the pathology, with both protocols (p<0.001).
dc.description.abstractDespite the statistical differences, there was a significant correlation in response evaluation between the two protocols. The pathological results were moderately correlated with both protocols, with SP slightly higher. However, the residual maximum median diameters were smaller than the pathology with both protocols. These results may limit the use of AP in evaluating the local extent of the tumor, especially in patients who will undergo breast-conserving surgery.
dc.identifier.pubmed35209823
dc.identifier.urihttps://hdl.handle.net/20.500.12645/38316
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsCC0 1.0 Universalen
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.subjectBreast
dc.subjectbreast neoplasm
dc.subjectdrug therapy
dc.subjectmagnetic resonance ımaging
dc.subjectneoadjuvant therapy
dc.subjectradiology
dc.titleAbbreviated and Standard Breast MRI in Neoadjuvant Chemotherapy Response Evaluation: A Comparative Study.
dc.typeArticle
dspace.entity.typePublication
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