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Increased P-Wave and QT Dispersions Necessitate Long-Term Follow-up Evaluation of Down Syndrome Patients With Congenitally Normal Hearts

dc.contributor.authorKaradeniz, Cem
dc.contributor.authorOzdemir, Rahmi
dc.contributor.authorDemir, Fikri
dc.contributor.authorYozgat, Yılmaz
dc.contributor.authorKucuk, Mehmet
dc.contributor.authorOner, Talia
dc.contributor.authorKaraarslan, Utku
dc.contributor.authorMese, Timur
dc.contributor.authorUnal, Nurettin
dc.contributor.institutionauthorYOZGAT, YILMAZ
dc.date.accessioned2020-10-22T18:11:43Z
dc.date.available2020-10-22T18:11:43Z
dc.date.issued2014-12-01T00:00:00Z
dc.description.abstractReports state that Down syndrome (DS) patients with congenitally normal hearts might experience the development of cardiac abnormalities such as cardiac autonomic dysfunction, valvular lesions, bradycardia, and atrioventricular block. However, the presence of any difference in terms of P-wave dispersion (PWd) and QT dispersion (QTd) was not evaluated previously. This study prospectively investigated 100 DS patients with structurally normal hearts and 100 age- and sex-matched healthy control subjects. Standard 12-lead electrocardiograms were used to assess and compare P-wave and QT durations together with PWd and QTd. The median age of the DS patients and control subjects was 48 months. Heart rates and P-wave and QT dispersions were significantly greater in the DS group than in the control group (113 +/- A 22.9 vs 98.8 +/- A 16.6 bpm, p < 0.001; 31.3 +/- A 9.5 vs 24 +/- A 8.6 ms, p < 0.001; and 46.6 +/- A 15.9 vs 26 +/- A 9.1 ms, p < 0.001, respectively). A positive correlation was found between PWd and age in the DS patients (p < 0.05; r = 0.2). All children with DS should be followed up carefully with electrocardiography in terms of increased P-wave and QT dispersions even in the absence of concomitant congenital heart disease for management of susceptibility to arryhthmias.
dc.identifier.citationKaradeniz C., Ozdemir R., Demir F., Yozgat Y., Kucuk M., Oner T., Karaarslan U., Mese T., Unal N., -Increased P-Wave and QT Dispersions Necessitate Long-Term Follow-up Evaluation of Down Syndrome Patients With Congenitally Normal Hearts-, PEDIATRIC CARDIOLOGY, cilt.35, ss.1344-1348, 2014
dc.identifier.doi10.1007/s00246-014-0934-2
dc.identifier.scopus84939898295
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24035
dc.identifier.wosWOS:000345333100006
dc.titleIncreased P-Wave and QT Dispersions Necessitate Long-Term Follow-up Evaluation of Down Syndrome Patients With Congenitally Normal Hearts
dc.typeArticle
dspace.entity.typePublication
local.avesis.id7d452b17-cb21-4306-81aa-18c7fe2b96a7
local.publication.isinternational1
relation.isAuthorOfPublicationac2e862c-9b22-4e55-980d-263d9c5fb35a
relation.isAuthorOfPublication.latestForDiscoveryac2e862c-9b22-4e55-980d-263d9c5fb35a
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