Publication:
Epidemiological Findings and Clinical and Magnetic Resonance Presentations in Subacute Sclerosing Panencephalitis

Simple item page
dc.contributor.authorCece, H.
dc.contributor.authorTokay, L.
dc.contributor.authorYildiz, S.
dc.contributor.authorKARAKAS, O.
dc.contributor.authorKARAKAS, E.
dc.contributor.authorIscan, AKIN
dc.contributor.institutionauthorİŞCAN, AKIN
dc.date.accessioned2020-10-29T13:04:42Z
dc.date.available2020-10-29T13:04:42Z
dc.date.issued2011-03-01T00:00:00Z
dc.description.abstractSubacute sclerosing panencephalitis (SSPE) is a rare, progressive, inflammatory neurodegenerative disease. This study investigated the relationships of clinical stage with epidemiological and magnetic resonance imaging (MRI) findings in SSPE by retrospective review of 76 cases (57 male) diagnosed by typical periodic electroencephalographic features, clinical symptoms and elevated measles antibody titre in cerebrospinal fluid. Clinical stage at diagnosis was I or II in 48 patients, III in 25 and IV in three. Prominent findings at presentation were atonic/myoclonic seizures (57.9%) and mental deterioration with behaviour alteration (30.3%). Frequent MRI findings (13 - 32 patients) were subcortical, periventricular and cortical involvement and brain atrophy; the corpus callosum, basal ganglia, cerebellum and brainstem were less frequently involved. Five patients had pseudotumour cerebri. Cranial MRI at initial diagnosis was normal in 21 patients (19 stage I/II, two stage III/IV). Abnormal MRI findings were significantly more frequent in the later stages, thus a normal initial cranial MRI does not exclude SSPE, which should, therefore, be kept in mind in childhood demyelinating diseases even when the presentation is unusual.
dc.identifier.citationCece H., Tokay L., Yildiz S., KARAKAS O., KARAKAS E., Iscan A., -Epidemiological Findings and Clinical and Magnetic Resonance Presentations in Subacute Sclerosing Panencephalitis-, JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, cilt.39, ss.594-602, 2011
dc.identifier.doi10.1177/147323001103900228
dc.identifier.scopus79955649047
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25060
dc.identifier.wosWOS:000291142200028
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleEpidemiological Findings and Clinical and Magnetic Resonance Presentations in Subacute Sclerosing Panencephalitis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id03ede279-398f-4636-84f1-d083725c7c7d
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication12538a20-d5a6-4246-ab37-58afe7bbae72
relation.isAuthorOfPublication.latestForDiscovery12538a20-d5a6-4246-ab37-58afe7bbae72
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
Files
Collections
Silinecekler