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The role of plasma exchange in hypertriglyceridemia-induced acute pancreatitis

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dc.contributor.authorKoçhan, K
dc.contributor.authorŞentürk, H
dc.contributor.authorKöker, İH
dc.contributor.authorGülen, B
dc.contributor.authorİnce, ALİ TÜZÜN
dc.contributor.institutionauthorBİBERCİ KESKİN, ELMAS
dc.contributor.institutionauthorKOÇHAN, KORAY
dc.contributor.institutionauthorKÖKER, İBRAHİM HAKKI
dc.contributor.institutionauthorİNCE, ALİ TÜZÜN
dc.contributor.institutionauthorŞENTÜRK, HAKAN
dc.date.accessioned2020-01-16T22:51:37Z
dc.date.available2020-01-16T22:51:37Z
dc.date.issued2019-06-01T00:00:00Z
dc.description.abstractBackground Hypertriglyceridemia (HTG)-induced acute pancreatitis (AP) leads to higher morbidity and mortality compared with other etiologies. The role of plasma exchange (PE) in this context is still not well established. We aimed to assess the clinical outcomes of patients with HTG-induced AP who underwent PE and compare it with those who did not. Patients and methods We retrospectively evaluated the data of patients who were admitted with HTG-induced AP between January 2013 and May 2018. The endpoint of the study was to assess the clinical outcomes, which included complication rates, mortality, and pancreatitis recurrence rate. Results Overall, 41 patients were included in the final analysis. Of these, 12 (29.2%) underwent PE. Patients undergoing PE had more severe pancreatitis on the basis of the Japanese Severity Score [10 (83.3%) vs. 14 (48.3%), P=0.03, respectively). Although mortality was higher in patients who underwent PE [three (25.0%) vs. zero, P<0.01, respectively], there was no difference in terms of complications and recurrence rates. Over a median 21 months of follow-up, 11 (26.8%) patients had recurrent AP. Conclusion Although PE effectively reduced plasma triglyceride levels, there was no decrease in mortality or recurrences.
dc.identifier.citationBiberci K., Koçhan K., Köker İ., Gülen B., İnce A. T. , Şentürk H., -The role of plasma exchange in hypertriglyceridemia-induced acute pancreatitis-, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.31, ss.674-677, 2019
dc.identifier.doi10.1097/meg.0000000000001399
dc.identifier.pubmed30896552
dc.identifier.scopus85065051673
dc.identifier.urihttps://openaccess.bezmialem.edu.tr/handle/20.500.12645/13359
dc.identifier.wosWOS:000466784700004
dc.language.isoen
dc.titleThe role of plasma exchange in hypertriglyceridemia-induced acute pancreatitis
dc.typeArticle
dspace.entity.typePublication
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