Publication: Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis
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WALOCHNIK, Julia
OBWALLER, Andreas
Vural, Ayse
DURSUN, AYHAN
ARICI, MUSTAFA KEMAL
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BackgroundIn this study, a series of compounds - miltefosine, polyhexamethylene biguanide, chlorhexidine and propamidine isethionate - and combinations of the latter three agents with miltefosine were prepared and used in a rat model for the topical treatment of Acanthamoeba keratitis.
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POLAT Z., WALOCHNIK J., OBWALLER A., Vural A., DURSUN A., ARICI M. K. , -Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis-, CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, cilt.42, ss.151-158, 2014