Publication:
Mitral Valve Lymphoma: An Unusual Cause of Embolic Strokes

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Oak A.
Arain A.
Rahman U.
YILMAZ S.
Suben J.
Kilic A.

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An 80-year-old woman with a history of non-Hodgkin lymphoma and branch retinal artery occlusion presented with acute visual changes and received a diagnosis of multifocal embolic cerebral infarcts. Cardiac imaging revealed a mobile left atrial mass on the mitral valve. Surgical excision was undertaken because of the high risk of recurrent embolization and strokes. Histopathologic examination demonstrated chronic lymphocytic leukemia/small lymphocytic lymphoma within a fibrinous and calcified matrix. This case illustrates a rare intracardiac manifestation of lymphoma serving as a cardioembolic source and highlights the importance of considering hematologic malignant disease in the differential diagnosis of intracardiac masses.

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Oak A., Arain A., Rahman U., YILMAZ S., Suben J., Kilic A., "Mitral Valve Lymphoma: An Unusual Cause of Embolic Strokes", Annals of Thoracic Surgery Short Reports, 2025

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