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Measurement of red blood cell aggregation in disposable capillary tubes

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dc.contributor.authorBaskurt, Oguz K.
dc.contributor.authorUyuklu, MEHMET
dc.contributor.authorÖZDEM, SEBAHAT
dc.contributor.authorMeiselman, Herbert J.
dc.contributor.institutionauthorÜYÜKLÜ, MEHMET
dc.date.accessioned2020-10-29T22:41:10Z
dc.date.available2020-10-29T22:41:10Z
dc.date.issued2011-01-01T00:00:00Z
dc.description.abstractA new method is described in this paper that allows measurement of red blood cell (RBC) aggregation indexes in disposable glass tubes within minutes. Light transmission through the RBC suspension filled into a microhematocrit capillary at stasis is recorded during RBC aggregation; a novel method assures an initial dispersion of aggregates in the capillary. The resulting light transmittance-time data are analyzed to calculate various parameters. Measurement of erythrocyte sedimentation rate (ESR) and RBC aggregation using well established methods and the newly developed capillary tube aggregometer in blood samples with a wide range of RBC aggregation indicated significant correlations between these parameters. Additionally, light transmittance during complete disaggregation allows estimating hematocrit, thereby enabling hematocrit correction of the measured and calculated parameters. The newly developed capillary tube RBC aggregometer is suitable for use as a method to rapidly monitor disease activity and the acute phase response, especially at the point-of-care (e. g., health care facilities, physician-s office) and for field studies.
dc.identifier.citationBaskurt O. K. , Uyuklu M., ÖZDEM S., Meiselman H. J. , -Measurement of red blood cell aggregation in disposable capillary tubes-, CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, cilt.47, ss.295-305, 2011
dc.identifier.doi10.3233/ch-2011-1411
dc.identifier.scopus79959225053
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26686
dc.identifier.wosWOS:000292265100007
dc.titleMeasurement of red blood cell aggregation in disposable capillary tubes
dc.typeArticle
dspace.entity.typePublication
local.avesis.idbbfe1a5b-4892-470e-b7cf-8e3c235f3ef1
local.publication.isinternational1
relation.isAuthorOfPublicationbc1199b5-be6a-43cc-9b25-7e47066119cc
relation.isAuthorOfPublication.latestForDiscoverybc1199b5-be6a-43cc-9b25-7e47066119cc
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