Publication:
Comparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury

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dc.contributor.authorKarik, Unal
dc.contributor.authorDemirbolat, Ilker
dc.date.accessioned2020-06-05T20:59:47Z
dc.date.available2020-06-05T20:59:47Z
dc.date.issued2020-05-14T04:00:00Z
dc.description.abstractThe aim of the present study was to investigate the therapeutic effects of 660-nm and 880-nm photobiomodulation therapy (PBMT) following inferior alveolar nerve (IAN) crush injury. Following the nerve crush injuries of IAN, 36 Wistar rats were randomly divided into three groups as follows: (1) control, (2) 660-nm PBMT, and (3) 808-nm PBMT (GaAlAs laser, 100 J/cm(2), 70 mW, 0.028-cm(2) beam). PBMT was started immediately after surgery and performed once every 3 days during the postoperative period. At the end of the 30-day treatment period, histopathological and histomorphometric evaluations of tissue sections were made under a light and electron microscope. The ratio of the inner axonal diameter to the total outer axonal diameter (g-ratio) and the number of axons per square micrometer were evaluated. In the 808-nm PBMT group, the number of nerve fibers with suboptimal g-ratio ranges of 0-0.49 (p < 0.001) is significantly lower than expected, which indicates better rate of myelinization in the 808-nm PBMT group. The number of axons per square micrometer was significantly higher in the 808-nm PBMT group when compared with the control (p < 0.001) and 660-nm PBMT group (p = 0.010). The data and the histopathological investigations suggest that the PBMT with the 808-nm wavelength along with its settings was able to enhance IAN regeneration after nerve crush injury.
dc.identifier.citationDİKER N., Aytac D., Helvacioglu F., Oguz Y., -Comparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury-, LASERS IN MEDICAL SCIENCE, cilt.35, ss.413-420, 2020
dc.identifier.doi10.1007/s10103-019-02838-w
dc.identifier.pubmed31273571
dc.identifier.scopus85068829803
dc.identifier.urihttps://hdl.handle.net/20.500.12645/18067
dc.identifier.wosWOS:000513211100014
dc.language.isoen
dc.titleComparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury
dc.typeArticle
dspace.entity.typePublication
local.avesis.id6556fb1c-687c-4636-a7e6-e74734ad0805?
local.publication.isinternational1
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