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Evaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolites

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dc.contributor.authorErtas, Abdulselam
dc.contributor.authorGoeren, AHMET CEYHAN
dc.contributor.authorHasimi, Nesrin
dc.contributor.authorTolan, Veysel
dc.contributor.authorKolak, Ufuk
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2020-10-29T23:16:56Z
dc.date.available2020-10-29T23:16:56Z
dc.date.issued2015-01-01T00:00:00Z
dc.description.abstractThe aim of the present study was to determine the chemical structures of the isolated compounds, the essential oil and fatty acid compositions of Mentha longifolia subsp. noeana with their biological activities. Ursolic acid (1), uvaol (2), stigmast-5-ene-3 beta-yl formate (3), stigmast-5-en-3-one (4), beta-sitosterol (5), bis(2ethylhexyl) benzene-1,2-dicarboxylate (6), hexacosyl (E)-ferulate (7) and 5-hydroxy-6,7,3-,4--tetramethoxy flavone (8) were obtained from the aerial parts. The compounds (2-4, 6, 7) were isolated for the first time from a Mentha species. Palmitic acid (40.8%) was the major component of the non-polar fraction obtained from the petroleum ether extract. Pulegone (32.3%) was the main constituent of the essential oil which exhibited strong butyrylcholinesterase inhibitory activity (77.36 +/- 0.29%), moderate antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans. The methanol extract showed 80% inhibition of lipid peroxidation, and the acetone extract possessed moderate DPPH free radical scavenging activity (60% inhibition) at 100 mu g/mL.
dc.identifier.citationErtas A., Goeren A. C. , Hasimi N., Tolan V., Kolak U., -Evaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolites-, RECORDS OF NATURAL PRODUCTS, cilt.9, ss.105-115, 2015
dc.identifier.scopus84908261496
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26977
dc.identifier.wosWOS:000350973300009
dc.titleEvaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolites
dc.typeArticle
dspace.entity.typePublication
local.avesis.idd8ab1a94-5420-4890-bb24-deb518a40516
local.publication.goal12 - Sorumlu Üretim ve Tüketim
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isGoalOfPublication97c265bd-2887-4843-9972-f4194480415d
relation.isGoalOfPublication.latestForDiscovery97c265bd-2887-4843-9972-f4194480415d
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