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Bioactive constituents of Salvia chrysophylla Stapf

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dc.contributor.authorButun, Burcu
dc.contributor.authorYapar, Gönül
dc.contributor.authorDirmenci, Tuncay
dc.contributor.authorTopcu, Gulacti
dc.contributor.institutionauthorBÜTÜN, BURCU
dc.contributor.institutionauthorTOPÇU, GÜLAÇTI
dc.date.accessioned2020-10-29T19:25:53Z
dc.date.available2020-10-29T19:25:53Z
dc.date.issued2013-03-01T00:00:00Z
dc.description.abstractThe dichloromethane extract of the aerial parts of Salvia chrysophylla Stapf (Lamiaceae), which is an endemic species to south-western Anatolia, was studied for non-volatile secondary metabolites for the first time in this study. Structures of the isolated compounds were elucidated as sclareol, -sitosterol, salvigenin, oleanolic acid and ursolic acid. The lipid peroxidation inhibitory activity and the DPPH free radical scavenging activity of the pure isolates were investigated to establish their antioxidant potential. Their anticholinesterase activity was carried out by the Ellman assay against both enzymes, acetylcholinesterase (AChE) and butyrylcholinesterase, and diterpene sclareol exhibited fairly good activity against both the enzymes while the two triterpenoids oleanolic and ursolic acids exhibited selective activity against AChE.
dc.identifier.citationButun B., Yapar G., Dirmenci T., Topcu G., -Bioactive constituents of Salvia chrysophylla Stapf-, NATURAL PRODUCT RESEARCH, cilt.27, ss.438-447, 2013
dc.identifier.doi10.1080/14786419.2012.734820
dc.identifier.scopus84875217673
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25800
dc.identifier.wosWOS:000315793600021
dc.titleBioactive constituents of Salvia chrysophylla Stapf
dc.typeArticle
dspace.entity.typePublication
local.avesis.id4af1555c-9eb6-475b-bc25-ade3a102e7ed
local.publication.isinternational1
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relation.isAuthorOfPublication3c94748e-c303-4294-ad67-c5a0739628e5
relation.isAuthorOfPublication.latestForDiscovery3c94748e-c303-4294-ad67-c5a0739628e5
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