Publication:
The impact of COVID-19 on familial Mediterranean fever: a nationwide study

dc.contributor.authorGünendi, Zafer
dc.contributor.authorYurdakul, Fatma Gül
dc.contributor.authorBodur, Hatice
dc.contributor.authorCengiz, Ahmet Kıvanç
dc.contributor.authorUçar, Ülkü
dc.contributor.authorÇay, Hasan Fatih
dc.contributor.authorŞen, Nesrin
dc.contributor.authorKeskin, Yaşar
dc.contributor.authorGürer, Gülcan
dc.contributor.authorMelikoğlu, Meltem Alkan
dc.contributor.authorAltıntaş, Duygu
dc.contributor.authorDeveci, Hülya
dc.contributor.authorBaykul, Merve
dc.contributor.authorNas, Kemal
dc.contributor.authorÇevik, Remzi
dc.contributor.authorKarahan, Ali Yavuz
dc.contributor.authorToprak, Murat
dc.contributor.authorKetenci, Sertaç
dc.contributor.authorNayimoğlu, Mehmet
dc.contributor.authorSezer, İlhan
dc.contributor.authorDemir, Ali Nail
dc.contributor.authorEcesoy, Hilal
dc.contributor.authorDuruöz, Mehmet Tuncay
dc.contributor.authorYurdakul, Ozan Volkan
dc.contributor.authorSarıfakıoğlu, Ayşe Banu
dc.contributor.authorAtaman, Şebnem
dc.contributor.institutionauthorKESKİN, YAŞAR
dc.contributor.institutionauthorYURDAKUL, OZAN VOLKAN
dc.date.accessioned2021-05-26T20:59:05Z
dc.date.available2021-05-26T20:59:05Z
dc.date.issued2021-05-25T00:00:00Z
dc.description.abstractThe study aimed to evaluate the impact of the coronavirus disease 2019 (COVID-19) in patients with familial Mediterranean fever (FMF) and to assess the relationships between FMF characteristics and severe COVID-19 outcomes such as hospitalization. The study was planned within a national network of 21 different centers. Demographics, FMF-related clinical and genetic characteristics, and COVID-19 outcomes were obtained. A total of 822 patients with FMF (mean age of 36 years) were included in the study. Fifty-nine of them (7%) had a COVID-19 diagnosis confirmed by real-time PCR test or chest CT findings. Most FMF patients with COVID-19 (58) had mild and moderate disease activity. All patients were on colchicine treatment. However, 8 of them (13.6%) were not compliant with colchicine use and 9 of them (15.3%) were colchicine resistant. Twelve FMF patients with COVID-19 were hospitalized. There were 4 patients requiring oxygen support. COVID-19 related complications were observed in 2 patients (1 thromboembolism, 1 acute respiratory distress syndrome). Hospitalized COVID-19 patients with FMF were older than non-hospitalized patients (median ages: 51 and 31 years, respectively; p: 0.002). Other FMF-related characteristics were similar between the groups. FMF-related characteristics were not found to be associated with poor outcomes in COVID-19. Thus, FMF may not be a risk factor for poor COVID-19 outcomes.
dc.identifier.doi10.1007/s00296-021-04892-6
dc.identifier.pubmed34032894
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28923
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectFamilial Mediterranean fever
dc.subjectRheumatic diseases
dc.subjectColchicine
dc.subjectHospitalization
dc.subjectPoor outcomes
dc.titleThe impact of COVID-19 on familial Mediterranean fever: a nationwide study
dc.typeArticle
dspace.entity.typePublication
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local.publication.goal03 - Sağlık ve Kaliteli Yaşam
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