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Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) - profiling of phenolic compounds by LC-HRMS

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dc.contributor.authorBingol, Zeynebe
dc.contributor.authorKızıltaş, Hatice
dc.contributor.authorGÖREN, AHMET CEYHAN
dc.contributor.authorKose, Leyla Polat
dc.contributor.authorTopal, Meryem
dc.contributor.authorDURMAZ, LOKMAN
dc.contributor.authorGulcin, İlhami
dc.contributor.authorAlwasel, Saleh H.
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2021-07-06T20:59:09Z
dc.date.available2021-07-06T20:59:09Z
dc.date.issued2021-05-01T00:00:00Z
dc.description.abstractIn order to evaluate the antioxidant activity of evaporated ethanolic extract (EESB) and lyophilized water extract (WESB) of Shaggy bindweed (Convulvulus betonicifolia Mill. Subs), some putative antioxidant methods such as DPPH. scavenging activity, ABTS(center dot)(-) scavenging effect, ferric ions (Fe3+) reduction method, cupric ions (Cu2+) reducing capacity, and ferrous ions (Fe2+) binding activities were separately performed. Also, ascorbic acid, alpha-tocopherol and BHT were used as the standard compounds. Additionally, some phenolic compounds that responsible for antioxidant abilities of EESB and WESB were screened by liquid chromatography-high resolution mass spectrometry (LC-HRMS). At the same concentration, EESB and WESB demonstrated effective antioxidant abilities when compared to standards. In addition, EESB demonstrated IC50 values of 1.946 mu g/mL against acetylcholinesterase (AChE), 0.815 mu g/mL against alpha-glycosidase and 0.675 mu g/mL against alpha-amylase enzymes.
dc.identifier.doi10.1016/j.heliyon.2021.e06986
dc.identifier.pubmed34027185
dc.identifier.scopus85105537391
dc.identifier.urihttp://hdl.handle.net/20.500.12645/29023
dc.identifier.wosWOS:000663597700003
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntioxidant activity
dc.subjectConvulvulus betonicifolia
dc.subjectLC-HRMS
dc.subjectPolyphenol content
dc.subjectShaggy bindweed
dc.titleAntidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) - profiling of phenolic compounds by LC-HRMS
dc.typeArticle
dspace.entity.typePublication
local.avesis.id906f2f4c-c965-4cd1-9387-25f17c9c03e2
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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