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Organophosphate induced delayed neuropathy: a case report

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dc.contributor.authorYalbuzdag, Seniz Akcay
dc.contributor.authorInce, Buğra
dc.contributor.authorKaratepe, Altinay Goksel
dc.contributor.authorSengul, Ilker
dc.contributor.authorKaya, Taciser
dc.contributor.institutionauthorİNCE, BUĞRA
dc.date.accessioned2021-02-03T20:59:10Z
dc.date.available2021-02-03T20:59:10Z
dc.date.issued2017-03-01T00:00:00Z
dc.description.abstractIn this paper, we present the case of a 27-year-old male patient who was admitted to our clinic with bilateral drop foot and spastic paraplegia after the ingestion of organophosphate (chlorpyrifos) and diagnosed with organophosphate induced delayed neuropathy (OPIDN). Patellar deep tendon reflexes were hyperactive, Achilles reflexes were absent, and patellar clonus were present bilaterally at the neurological examination. The results of electrophysiological studies were compatible with motor axonal polyneuropathy. The patient was admitted to the neurological rehabilitation program and was able to ambulate using a pair of plastic ankle-foot orthosis and walker. Six months after the baseline, Botulinum toxin type A was injected bilaterally to adductor magnus (100 U) and adductor longus (50 U) muscles. After the Botulinum toxin injection, spasticity of the hip adductor muscles was decreased from grade 4 to grade 3 according to the modified Ashworth scale. By the end of seven-month follow-up period, partial improvement was observed in the muscle strength of the patient, and he became independent in his daily activities. In this article, we discuss possible mechanisms of OPIDN, on the basis of clinical features and the rehabilitation process of a 27-year-old male patient diagnosed with OPIDN, with a review of the current literature.
dc.identifier.citationYalbuzdag S. A. , Ince B., Karatepe A. G. , Sengul I., Kaya T., -Organophosphate induced delayed neuropathy: a case report-, TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION, cilt.63, ss.88-91, 2017
dc.identifier.doi10.5606/tftrd.2017.13549
dc.identifier.scopus85016197109
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28285
dc.identifier.wosWOS:000400722700014
dc.titleOrganophosphate induced delayed neuropathy: a case report
dc.typeArticle
dspace.entity.typePublication
local.avesis.id9e8776cb-1e8e-45dc-b27a-bb88e518150e
local.publication.isinternational1
relation.isAuthorOfPublication2cdef8c9-20b0-4c4f-8465-9f0789390985
relation.isAuthorOfPublication.latestForDiscovery2cdef8c9-20b0-4c4f-8465-9f0789390985
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