This research was carried out to determine women's health beliefs about HPV and HPV vaccine. This cross-sectional study was conducted with 300 women between September-December 2019 in the obstetrics outpatient clinic of a Private University Hospital on the European Side of Istanbul. In data collection; Sociodemographic characteristics information form, Human Papillomavirus (HPV) Infection Knowledge Scale, and Health Belief Model for Human Papilloma Virus Infection and It's Vaccination Scale were used. While evaluating the study data, besides descriptive statistical methods (mean, standard deviation, frequency), Student-t test was used for comparing normally distributed variables between two groups in evaluating quantitative data, and Mann-Whitney U test was used for comparisons of variables not showing normal distribution between two groups. One-way analysis of variance (ANOVA) test was used to compare normally distributed data between more than two groups, and Tukey HSD and Bonferonni post hoc tests were used to determine which group caused the difference. The average age of the women participating in the study was found to be 35.16 ± 9.526. When the sociodemographic characteristics of the women were examined, 34.3% were between the ages of 31-40, 46% were undergraduate, 29% were unmarried and 31.7% of them partners' education status were postgraduate, 69.3% 50.3% of them defined their economic situation as good. When the health behaviors of the women included in the study were examined, 88.3% had heard of pap-smear test before, 75.3% had pap-smear test before, 33.7% had pap-smear test every year. It was determined that 72.3% had heard of HPV infection before, but 69.7% had not had HPV test before, 62% had heard of HPV vaccine, but 90.3% had not had HPV vaccine. HPV Infection Knowledge Scale mean score of women was found to be 3.73 ± 2.457. HPV infection knowledge scale mean score was found to be high in women who has licence education, partners' education status was postgraduate, have heard the pap-smear test, have heard the HPV test, have had the HPV test, have had HPV before, have had HPV vaccine, have had HPV vaccine, have had abnormal results in cytological tests (p<0,001). In the health belief model of the HPV and HPV vaccine of women, the perception of benefit is higher in women who have a license level, have a good economic situation, hear the pap-smear test, hear the HPV test, have HPV vaccine, have HPV vaccine, have a sexually transmitted disease and using alcohol (p<0,05). In the health belief model of HPV and HPV vaccine of women, the perception of sensitivity was higher in women with a license level of education, have heard the pap-smear test, have heard the HPV test, have had the HPV test, have heard the HPV vaccine, have had the HPV vaccine, and using alcohol (p<0,05). In the health belief model of the HPV and HPV vaccine of women, the perception of severity was higher in women who have a good economic situation, have heard the pap-smear test, have heard the HPV test, have had the HPV test, have heard the HPV vaccine and using alcohol (p<0,05). In the health belief model of the HPV and HPV vaccine of women, the perception of barriers was lower in women with licence education status, partners' education status was postgraduate, a good economic situation, have heard pap-smear test, have had pap-smear test, have had HPV vaccine and using alcohol (p<0,05). In the study, a positive significant relationship was found between the HPV infection knowledge scale and the benefit perception, susceptibility perception and severity perception of HPV and HPV vaccine, while no significant relationship was found between the perception of barriers.