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Investigation of the Relationship between Serum Levels of Cotinine and the Renal Function in Active and Passive Smokers

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dc.contributor.authorDulger, Haluk
dc.contributor.authorDonder, Ahmet
dc.contributor.authorŞekeroğlu, Mehmet Ramazan
dc.contributor.authorErkoc, Reha
dc.contributor.authorOzbay, Bulent
dc.date.accessioned2020-10-21T20:29:32Z
dc.date.available2020-10-21T20:29:32Z
dc.date.issued2011-01-01T00:00:00Z
dc.description.abstractObjective: We have investigated the effects of active and passive smoking on renal functions in terms of glomerular filtration rate, microalbuminuria, and beta-2 microglobulin excretion. Design and method: The volunteers included in this study were classified into three groups as active smokers (n = 24), passive smokers (n = 20), and controls (n = 20). Blood and urine samples were collected from all groups. Serum glucose, urea, creatinine, and cotinine levels in the collected blood samples were measured. Also, microalbumin, beta-2 microglobulin, and creatinine levels were measured in the collected urine samples. Results: Serum cotinine levels were found to be higher in both passive and active smokers when compared with controls (p < 0.01), whereas urinary microalbumin and creatinine levels were significantly higher in active smokers (p < 0.01). The urinary microalbumin/creatinine ratio was significantly increased in both active and passive smokers compared with controls. Conclusion: The kidney and the glomerular functions may be affected even by passive smoking. In addition, increased microalbumin/creatinine ratio may be a sign of increased atherosclerosis risk in these persons.
dc.identifier.citationDulger H., Donder A., Şekeroğlu M. R. , Erkoc R., Ozbay B., -Investigation of the Relationship between Serum Levels of Cotinine and the Renal Function in Active and Passive Smokers-, RENAL FAILURE, cilt.33, ss.475-479, 2011
dc.identifier.doi10.3109/0886022x.2011.577922
dc.identifier.pubmed
dc.identifier.scopus79956290611
dc.identifier.urihttp://hdl.handle.net/20.500.12645/23501
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.3109/0886022X.2011.577922
dc.identifier.wosWOS:000290670300002
dc.subjectSmoker
dc.titleInvestigation of the Relationship between Serum Levels of Cotinine and the Renal Function in Active and Passive Smokers
dc.typeArticle
dspace.entity.typePublication
local.avesis.id2021c65e-76d5-418d-b7ca-8013915f1b4a
local.publication.isinternational1
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