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Determination of Potential Drug-Drug Interactions Using Various Software Programs in a Community Pharmacy Setting

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dc.contributor.authorSANCAR, MESUT
dc.contributor.authorKasik, Aksa
dc.contributor.authorOKUYAN, BETÜL
dc.contributor.authorBatuhan, Sevda
dc.contributor.authorIzzettin, FİKRET VEHBİ
dc.contributor.institutionauthorİZZETTİN, FIKRET VEHBI
dc.date.accessioned2020-10-29T14:15:16Z
dc.date.available2020-10-29T14:15:16Z
dc.date.issued2019-03-01T00:00:00Z
dc.description.abstractObjectives: The aim of the present study was to compare various software programs in detecting potential drug-drug interactions in a community pharmacy setting. Materials and methods: Details of prescriptions were collected from 50 community pharmacies located in İstanbul in March and April 2015 (two days per week). From each pharmacy, the first 20 prescriptions that included more than one drug were collected to evaluate potential drug-drug interactions. The following software programs were utilized to detect potential drug-drug interactions: micromedexsolutions.com, medscape.com, and drugs.com. The number of potential interactions detected by the software programs was determined. Results: At least one potential drug-drug interaction was detected in 39.2% of the 1000 prescriptions by one of the software programs. According to the rates of total drug-drug interactions gathered from various software programs, these programs gave the following results: medscape.com 33.3%, drugs.com 31.3%, and micromedexsolutions.com 21.2%. Conclusion: After comparing different software programs, the potential drug-drug interactions found by the programs proved to be different. Therefore, we recommend that pharmacists confirm with a different program before making a decision when they detect clinically significant potential drug-drug interactions.
dc.identifier.citationSANCAR M., Kasik A., OKUYAN B., Batuhan S., Izzettin F. V. , -Determination of Potential Drug-Drug Interactions Using Various Software Programs in a Community Pharmacy Setting-, TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.16, ss.14-19, 2019
dc.identifier.doi10.4274/tjps.30932
dc.identifier.pubmed32454689
dc.identifier.scopus85062002676
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25297
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/32454689/
dc.identifier.wosWOS:000454625100003
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDrug–drug interactions
dc.subjectPharmacist
dc.titleDetermination of Potential Drug-Drug Interactions Using Various Software Programs in a Community Pharmacy Setting
dc.typeArticle
dspace.entity.typePublication
local.avesis.id2273de10-b4e5-4f20-bd6b-6358df505167
local.publication.isinternational1
relation.isAuthorOfPublicationcc4fb95b-daac-4065-9eea-9b57f6b44654
relation.isAuthorOfPublication.latestForDiscoverycc4fb95b-daac-4065-9eea-9b57f6b44654
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