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The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea

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dc.contributor.authorKILICARSLAN, Rukiye
dc.contributor.authorAlkan, ALPAY
dc.contributor.authorSharifov, RASUL
dc.contributor.authorAkkoyunlu, MUHAMMED EMİN
dc.contributor.authorAralasmak, AYŞE
dc.contributor.authorKOCER, Abdulkadir
dc.contributor.authorKART, Levent
dc.contributor.institutionauthorALKAN, ALPAY
dc.contributor.institutionauthorSHARIFOV, RASUL
dc.contributor.institutionauthorAKKOYUNLU, MUHAMMED EMİN
dc.contributor.institutionauthorARALAŞMAK, AYŞE
dc.date.accessioned2019-10-05T21:59:29Z
dc.date.available2019-10-05T21:59:29Z
dc.date.issued2014-01-01
dc.description.abstractPurpose: We investigated diffusion alterations in specific regions of the brain in morbid obese, obese, and nonobese OSA patients and searched whether there is a correlation between BMI and ADC values. Materials and methods: DWIs of 65 patients with OSA were evaluated. The patients were classified according to BMI as morbid obese (n = 16), obese (n = 27), and nonobese (control, n = 22) groups. ADC measurements were performed from 24 different regions of the brain in each patient. The relationship of BMI with ADC values was searched. Results: The ADC values in hypothalamus, insular cortex, parietal cortex, caudate nucleus, frontal white matter, and posterior limb of internal capsule were all increased in obese patients (n = 43) compared to control group. The ADC values of midbrain, hypothalamus, orbitofrontal cortex, and parietal cortex were significantly increased in morbid obese compared to obese patients. In obese patients, the degree of BMI was positively correlated with ADC values of orbitofrontal cortex, parietal cortex, and hypothalamus. Conclusion: We observed increasing brain vasogenic edema with increasing BMI, suggesting that the main reason of brain diffusion alteration in patients with OSA could be obesity related.en
dc.identifier
dc.identifier.citationKILICARSLAN R., Alkan A., Sharifov R., Akkoyunlu M. E. , Aralasmak A., KOCER A., KART L., -The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea-, SCIENTIFIC WORLD JOURNAL, 2014
dc.identifier.doi10.1155/2014/768415
dc.identifier.pubmed24729752
dc.identifier.scopus84898915799
dc.identifier.urihttps://hdl.handle.net/20.500.12645/8627
dc.identifier.wosWOS:000332892400001
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleThe Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameKAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
local.avesis.idd705d48a-c11c-4ba4-bf85-de8eb0407799
local.avesis.response8503
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
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