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MTHFR Gene Polymorphisms in Bladder Cancer in the Turkish Population

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dc.contributor.authorIzmirli, Muzeyyen
dc.contributor.authorInandiklioglu, Nihal
dc.contributor.authorAbat, Deniz
dc.contributor.authorALPTEKİN, DAVUT
dc.contributor.authorDEMİRHAN, OSMAN
dc.contributor.authorTansug, Zuhtu
dc.contributor.authorBAYAZIT, YILDIRIM
dc.date.accessioned2020-10-21T20:04:16Z
dc.date.available2020-10-21T20:04:16Z
dc.date.issued2011-01-01T00:00:00Z
dc.description.abstractBladder cancer is the 9th most common cancer and is responsible for malignancy related death all on the world. Folate and folate related enzyme polymorphisms related to the cancer risk. The methylene tethrahydrofolate reductase (MTHFR) enzyme is folate related and association of bladder cancer and MTHFR gene. Our purpose was to assess the prevalence of MTHFR gene 677 CT and 1298 AC polymorphisms and Bladder cancer in Turkey. We intended that bladder cancer patients and controls and we used the Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) methods. The MTHFR gene C677T and A1298C polymorphisms were associated with an increased risk of bladder cancer in our population (For the MTHFR gene C677T polymorphism and A1298C polymorphism; p=0.0360.05 respectively). Consequently, the MTHFR gene C677T polymorphism augments the risk of bladder cancer in Turkey.
dc.identifier.citationIzmirli M., Inandiklioglu N., Abat D., ALPTEKİN D., DEMİRHAN O., Tansug Z., BAYAZIT Y., -MTHFR Gene Polymorphisms in Bladder Cancer in the Turkish Population-, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, cilt.12, ss.1833-1835, 2011
dc.identifier.pubmed22126575
dc.identifier.scopus84863920585
dc.identifier.urihttp://hdl.handle.net/20.500.12645/23308
dc.identifier.urihttp://journal.waocp.org/
dc.identifier.wosWOS:000299266500037
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCancer
dc.titleMTHFR Gene Polymorphisms in Bladder Cancer in the Turkish Population
dc.typeArticle
dspace.entity.typePublication
local.avesis.id04a2ad5f-a0f8-4f5d-a4e8-148bfe72510b
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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