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Effects of extracorporeal shock-wave lithotripsy directed at the parotid gland on oxidative stress parameters and some trace element levels in facial nerve of rats

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dc.contributor.authorKavak, Servet
dc.contributor.authorGarca, M. Fatih
dc.contributor.authorGecit, Ilhan
dc.contributor.authorMeral, Ismail
dc.contributor.authorCengiz, Nurettin
dc.contributor.authorDemir, Halit
dc.contributor.institutionauthorMERAL, İSMAİL
dc.date.accessioned2020-10-29T20:21:32Z
dc.date.available2020-10-29T20:21:32Z
dc.date.issued2012-04-01T00:00:00Z
dc.description.abstractIntroduction: This study was designed to assess the effect of extracorporeal shock-wave lithotripsy (ESWL) exposure of the parotid gland on oxidative stress and some trace element levels in the facial nerves of rats. Methods: Twelve male Wistar albino rats were divided into two groups, each consisting of 6 animals. The rats in the first group served as controls. The left parotid glands of animals in the second group were treated with 1000 18-kV shock waves while anesthetized with ketamine. The animals in both groups were euthanized 72 h after the ESWL treatment, and the right facial nerve was harvested for determination of oxidant/antioxidant status and trace element levels. Results: Lipid peroxidation product malondialdehyde (MDA) and antioxidant glutathione (GSH) levels increased, and the activities of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), decreased in the facial nerves of ESWL-treated rats. The levels of iron, lead, manganese, and cobalt increased, and magnesium, cadmium, and copper levels decreased. Conclusions: ESWL treatment of the parotid gland may increase lipid peroxidation and decrease antioxidant enzyme activity in adjacent tissues such as the facial nerve. It also causes a decrease or increase in many mineral levels of the facial nerve, which is an undesirable condition for normal physiological function. Muscle Nerve, 2012
dc.identifier.citationKavak S., Garca M. F. , Gecit I., Meral I., Cengiz N., Demir H., -Effects of extracorporeal shock-wave lithotripsy directed at the parotid gland on oxidative stress parameters and some trace element levels in facial nerve of rats-, MUSCLE & NERVE, cilt.45, ss.562-566, 2012
dc.identifier.doi10.1002/mus.22326
dc.identifier.scopus84860347550
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26007
dc.identifier.wosWOS:000301657000015
dc.titleEffects of extracorporeal shock-wave lithotripsy directed at the parotid gland on oxidative stress parameters and some trace element levels in facial nerve of rats
dc.typeArticle
dspace.entity.typePublication
local.avesis.id641dbdb2-e475-46e7-b396-3924463f455a
local.publication.isinternational1
relation.isAuthorOfPublication58058ee9-1440-480c-9817-c6b25d7ec008
relation.isAuthorOfPublication.latestForDiscovery58058ee9-1440-480c-9817-c6b25d7ec008
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