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The levels of visceral adipose tissue-derived serpin, omentin-1 and tumor necrosis factor-alpha in the gingival crevicular fluid of obese patients following periodontal therapy

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dc.contributor.authorBalli, UMUT
dc.contributor.authorDogan, Seyma Bozkurt
dc.contributor.authorDede, Figen Ongoz
dc.contributor.authorSertoglu, Erdim
dc.contributor.authorKeles, Gonca Cayir
dc.contributor.institutionauthorBALLI, UMUT
dc.date.accessioned2021-02-01T20:59:14Z
dc.date.available2021-02-01T20:59:14Z
dc.date.issued2016-12-01T00:00:00Z
dc.description.abstractThe aim of this clinical study was to determine levels of visceral adipose tissue-derived serpin (vaspin), omentin-1, and tumor necrosis factor-alpha (TNF-alpha) in the gingival crevicular fluid (GCF) of obese and non-obese periodontitis patients following nonsurgical periodontal therapy. Seventy-six subjects were separated into four groups according to periodontal and anthropometric measurements: a periodontal-healthy group, a chronic periodontitis (CP) group, a periodontal-healthy with obesity group, and a CP with obesity group. Nonsurgical periodontal treatment was administered to periodontitis patients. Before treatment and at 6 weeks after treatment, GCF samples were analyzed and clinical periodontal parameters were examined. Enzyme-linked immunosorbent assays were used to measure the levels of vaspin, omentin-1, and TNF-a. Obese and non-obese CP patients displayed higher levels of vaspin and TNF-alpha (P < 0.008), which declined following treatment (P< 0.025), and lower omentin levels (P <0.008), which increased after treatment (P < 0.025). There was a negative correlation between the total amount of vaspin and omentin-1 in all groups. Obese and non-obese patients had opposing levels of vaspin and omentin-1 in the GCF; therefore, these may represent diagnostic and prognostic indicators of periodontal disease and therapeutic outcome.
dc.identifier.citationBalli U., Dogan S. B. , Dede F. O. , Sertoglu E., Keles G. C. , -The levels of visceral adipose tissue-derived serpin, omentin-1 and tumor necrosis factor-alpha in the gingival crevicular fluid of obese patients following periodontal therapy-, JOURNAL OF ORAL SCIENCE, cilt.58, ss.465-473, 2016
dc.identifier.doi10.2334/josnusd.16-0212
dc.identifier.scopus85007328470
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28222
dc.identifier.wosWOS:000390087600003
dc.titleThe levels of visceral adipose tissue-derived serpin, omentin-1 and tumor necrosis factor-alpha in the gingival crevicular fluid of obese patients following periodontal therapy
dc.typeArticle
dspace.entity.typePublication
local.avesis.id159d868c-7f27-45ee-b7df-bc1d75f3c549
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication98da5869-ea4b-40c5-873f-9bbd29c50a23
relation.isAuthorOfPublication.latestForDiscovery98da5869-ea4b-40c5-873f-9bbd29c50a23
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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