Publication:
Electrocardiography and Drug Intoxication

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dc.contributor.authorTaşlıdere B.
dc.contributor.institutionauthorTAŞLIDERE, BAHADIR
dc.date.accessioned2023-01-05T23:58:38Z
dc.date.available2023-01-05T23:58:38Z
dc.date.issued2023-01-01
dc.description.abstractIntoxication is the deterioration of body functions due to different toxic substances. Poisoning by drugs constitutes an important part of all poisonings. Symptoms such as altered consciousness, tachycardia/bradycardia, or hypertension/hypotension may be seen because the cardiovascular system is affected. Changes in clinical findings and ECG may be revealed according to the degree of heart involvement. Rapid recognition and effective intervention by the emergency physician are of great importance. This review considers the use of ECG in the management of poisoned patients. Systematic evaluation of the ECG in a patient followed up with poisoning is essential for details that may be overlooked. Velocity, rhythm, intervals, and segments, QRS, wave morphologies, durations, ischemic changes should be followed carefully. When performing rhythm analysis, clues to drug cardiotoxicity should be sought in unstable patients. Are there ectopic beats on the EKG? The answer to this question may carry important clues. Automaticity caused by sympathomimetics may underlie ectopic beats. This may be the first sign of a problem caused by acute coronary syndrome or electrolyte disturbances. Is the rhythm supraventricular? or ventricular? Is bradycardia with AV block? Or without AV block? Is tachycardia narrow complex? Or is it a large complex? Answers to questions such as: For life-threatening rhythms, ventricular tachycardia, ventricular fibrillation, and complete AV-block, the guidelines developed should be followed, and first intervention should be made. Agents that can cause tachycardia; are sympathomimetics (methamphetamine), anticholinergics (antidepressants, antipsychotics), class 1A and 1C antidysrhythmics, and TCA. Agents that can cause bradycardia; calcium channel / beta blockers / digoxin (AV block), opioids / ethanol, organophosphates, lithium. Prolonging the PR interval may indicate beta-adrenergic antagonism, calcium channel antagonism, or digoxin poisoning. Typical ECG of TCA poisoning shows sinus tachycardia with first-degree AV block, wide QRS complexes, and positive R\" wave in aVR. The ECG should be taken and evaluated in patients presenting with poisoning within the first 10 minutes. Suppose the poisoning agent is an agent that influences the cardiovascular system. In that case, it should be kept in mind that continuous cardiac monitoring and control ECG evaluation should be performed in addition to the application of ECG.
dc.identifier.citationTaşlıdere B., "Electrocardiography and Drug Intoxication", Eurasian journal of toxicology, cilt.4, sa.3, ss.88-92, 2023
dc.identifier.doi10.51262/ejtox.1171416
dc.identifier.endpage92
dc.identifier.issue3
dc.identifier.startpage88
dc.identifier.urihttps://avesis.bezmialem.edu.tr/api/publication/831deb9a-d780-47e3-8d13-7715167a4118/file
dc.identifier.urihttps://hdl.handle.net/20.500.12645/34577
dc.identifier.volume4
dc.relation.ispartofEurasian journal of toxicology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectAcil Tıp
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectEmergency Medicine
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCERRAHİ
dc.subjectACİL TIP
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectSURGERY
dc.subjectEMERGENCY MEDICINE
dc.subjectAcil Tıp Hizmetleri
dc.subjectCerrahi
dc.subjectEmergency Medical Services
dc.subjectSurgery
dc.titleElectrocardiography and Drug Intoxication
dc.typearticle
dspace.entity.typePublication
local.avesis.id831deb9a-d780-47e3-8d13-7715167a4118
relation.isAuthorOfPublicationc3a1f40b-abfb-41fc-ac37-c541ff5cc173
relation.isAuthorOfPublication.latestForDiscoveryc3a1f40b-abfb-41fc-ac37-c541ff5cc173
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