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Comparison of the effects of ozone therapy and photobiomodulation on sciatic nerve injury in rats

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dc.contributor.authorGÜNAY CANPOLAT, DİLEK
dc.contributor.authorYÜCESOY, TÜRKER
dc.contributor.authorColpak, Halis Ali
dc.contributor.authorKAYA, ÖZLEM TUĞÇE
dc.contributor.authorKolbasi, Bircan
dc.contributor.authorSaraymen, Recep
dc.contributor.authorKaraturk, Habip
dc.contributor.authorKÜTÜK, NÜKHET
dc.contributor.authorCANPOLAT, MEHMET
dc.contributor.institutionauthorYÜCESOY, TÜRKER
dc.contributor.institutionauthorKÜTÜK, NÜKHET
dc.date.accessioned2021-12-21T20:59:14Z
dc.date.available2021-12-21T20:59:14Z
dc.date.issued2021-11-01T00:00:00Z
dc.description.abstractAim: Studies on drugs or alternative therapies are still the main treatment options for PNI. In this study, we aimed to research the effects of PBM and OT on nerve repair in a rat sciatic injury model. Material and Methods: 29 Wistar albino rats were divided into four groups: control (n = 2), sham (n = 9), OT (n = 9) and PBM (n = 9). After 30 days of surgery and treatments, tissue specimens and blood samples were taken for histological and biochemical processing. Histological evaluations were performed at light and electron microscopy levels. Myelin basic protein (MBP) and S100 from the rat serum were analysed also. Results: The OT and PBM groups had a significant increase in regeneration of the sciatic nerve in light microscopic evaluation. In the PBM and OT groups, Schwann cells (SC) around the axons and also axons with a thin myelin sheath were seen, regarded as signs of the myelination process in transmission electron microscopy (TEM) examinations. Discussion: OT and PBM both resulted in a good healing pattern for sciatic nerve injury in the rat model. Therefore, OT and PBM are considered to be simple and reliable alternative treatment methods for PNI.
dc.identifier.citationGÜNAY CANPOLAT D., YÜCESOY T., Colpak H. A. , KAYA Ö. T. , Kolbasi B., Saraymen R., Karaturk H., KÜTÜK N., CANPOLAT M., -Comparison of the effects of ozone therapy and photobiomodulation on sciatic nerve injury in rats-, ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, 2021
dc.identifier.doi10.4328/acam.20877
dc.identifier.urihttp://hdl.handle.net/20.500.12645/29827
dc.identifier.wosWOS:000729245600001
dc.titleComparison of the effects of ozone therapy and photobiomodulation on sciatic nerve injury in rats
dc.typeArticle
dspace.entity.typePublication
local.avesis.idf1a28129-b1cb-4eff-a35f-5da8a0daf057
local.publication.isinternational1
relation.isAuthorOfPublication193cbe86-c7d0-4ebc-8e97-778709d2354e
relation.isAuthorOfPublication908c31f8-027f-44c3-9992-1f8b42ac3367
relation.isAuthorOfPublication.latestForDiscovery193cbe86-c7d0-4ebc-8e97-778709d2354e
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