Publication:
Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?

dc.contributor.authorGok, Koray
dc.contributor.authorTakmaz, Taha
dc.contributor.authorKose, Osman
dc.contributor.authorTuten, Nevin
dc.contributor.authorAcikgoz, Abdullah Serdar
dc.contributor.authorBostanci, Mehmet Suhha
dc.contributor.authorOzden, Selcuk
dc.date.accessioned2023-05-16T14:40:48Z
dc.date.available2023-05-16T14:40:48Z
dc.date.issued2022-12-31T21:00:00Z
dc.description.abstractThe study aimed to investigate the effectiveness of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and platelet values in predicting intrahepatic cholestasis of pregnancy (ICP) in the first trimester, together with the aspartate aminotransferase/platelet ratio index (APRI) score.
dc.description.abstractThis study consisted of a patient group diagnosed with ICP (n=49) and a control group (n=62). Laboratory tests of both groups were analyzed retrospectively.
dc.description.abstractThe first-trimester APRI score and AST and ALT values were found to be statistically significantly higher than those of the control group. The platelet value was found to be statistically significantly lower in the study group, even though it was within the normal reference range.
dc.description.abstractThe first-trimester APRI score was found to be effective in predicting ICP. In addition, the first-trimester AST, ALT, and platelet values were found to be effective in predicting ICP diagnosed in the third trimester even though if not as much as the APRI score.
dc.identifier.doi10.14744/hf.2022.2022.0031
dc.identifier.pubmed36843897
dc.identifier.urihttps://hdl.handle.net/20.500.12645/37846
dc.language.isoen
dc.subjectAPRI score
dc.subjectintrahepatic cholestasis
dc.subjectprediction
dc.subjectpregnancy
dc.titleCan first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?
dspace.entity.typePublication
local.indexed.atPubMed

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