Publication:
Iron deficiency anemia and levels of oxidative stress induced by treatment modality

dc.contributor.authorAkarsu, Saadet
dc.contributor.authorDemir, Hatice
dc.contributor.authorSelek, ŞAHBETTİN
dc.contributor.authorOguzoncul, Ferdane
dc.contributor.institutionauthorSELEK, ŞAHABETTİN
dc.date.accessioned2020-10-29T14:01:56Z
dc.date.available2020-10-29T14:01:56Z
dc.date.issued2013-06-01T00:00:00Z
dc.description.abstractBackground The effects of iron deficiency anemia (IDA) and its treatment on plasma total antioxidant capacity (TAOC) were investigated. Methods Sixty patients with IDA and 20 healthy controls were divided into four subgroups: an oral (per os: PO) group (n = 20); an intramuscular (IM) group (n = 20); an intravenous (IV) group (n = 20); and the control group (n = 20). Blood samples were obtained from all patients before treatment, and at 24h, 7 days, 6 and 13 weeks after initiation of IDA therapy. Results TAOC in the IDA group was low when compared with the control group (P < 0.001). Although TAOC at 24h in the PO group was not different from the control group, the TAOC in the IM and IV groups was relatively lower (P < 0.001). The TAOC in the PO group at 7 days, and at 6 and 13 weeks was closest to the control group level. The mean TAOC in the IV group at 13 weeks was clearly lower relative to the PO and IM groups. Conclusions Oxidative stress was minimally induced with oral therapy, while IM and IV therapies induced higher levels of oxidative stress, in increasing order of intensity.
dc.identifier.citationAkarsu S., Demir H., Selek Ş., Oguzoncul F., -Iron deficiency anemia and levels of oxidative stress induced by treatment modality-, PEDIATRICS INTERNATIONAL, cilt.55, ss.289-295, 2013
dc.identifier.doi10.1111/ped.12054
dc.identifier.scopus84879325954
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25212
dc.identifier.wosWOS:000320620100017
dc.titleIron deficiency anemia and levels of oxidative stress induced by treatment modality
dc.typeArticle
dspace.entity.typePublication
local.avesis.id1898cb2e-d388-452f-8694-abf46059eedd
local.publication.isinternational1
relation.isAuthorOfPublication8eb7d539-8ea4-435c-830e-8ef630342c7d
relation.isAuthorOfPublication.latestForDiscovery8eb7d539-8ea4-435c-830e-8ef630342c7d

Files

Collections