Publication:
Effects of Different Concentrations of Injectable Collagenase Enzyme on Capsular Tissue Around Silicone Implants: A Preliminary Experimental Study for the Development of a New Treatment Strategy

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Date
2016-02-01T00:00:00Z
Authors
Yesiloglu, Nebil
Temiz, Gokhan
Sarici, Murat
YILDIZ, KEMALETTİN
Sirinoglu, Hakan
Guvercin, Emre
Akpinar, Ali Cem
Filinte, Gaye Taylan
FİLİNTE, DENİZ
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Research Projects
Sustainable Development Goals
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Abstract
In recent studies, collagen organization was blamed for the formation of capsular contracture which is still a challenging problem after silicone implant-based breast operations. In this study, effects of different concentrations of collagenase enzyme derived from Clostridium histolyticum on the capsular tissue formation around the silicone implants were investigated. The injectable form of collagenase has a routine clinical use in the treatment of both Dupuytren-s and Peyronie-s diseases.
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Yesiloglu N., Temiz G., Sarici M., YILDIZ K., Sirinoglu H., Guvercin E., Akpinar A. C. , Filinte G. T. , FİLİNTE D., -Effects of Different Concentrations of Injectable Collagenase Enzyme on Capsular Tissue Around Silicone Implants: A Preliminary Experimental Study for the Development of a New Treatment Strategy-, AESTHETIC PLASTIC SURGERY, cilt.40, ss.164-173, 2016